IL17 Receptor B anticorps (Extracellular Domain)

N° du produit ABIN360915

Cet anticorps anti-IL17 Receptor B est un anticorps Rat Monoclonal détectant IL17 Receptor B dans WB. Adapté pour Souris.

Aperçu rapide pour IL17 Receptor B anticorps (Extracellular Domain) (ABIN360915)

Antigène: IL17 Receptor B (IL17RB) (Interleukin 17 Receptor B (IL17RB))

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp IL17 Receptor B est non-conjugé

Application: Western Blotting (WB)

Clone: 9J28

Détail du produit anti-IL17 Receptor B anticorps

Épitope: Extracellular Domain

Specificité: This antibody detects Mouse IL-17BR. No cross activity with Mouse IL-17R.

Purification: Protein A/G Affinity Chromatography

Immunogène: Recombinant protein of IL-17B R extracellular domain.

Isotype: IgG2

Information d'application

Indications d'application: Western Blot: 1/500 - 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Reconstitution: Restore with 200 μL sterile PBS and the final concentration is 500 μg/mL.

Buffer: PBS without stabilizer

Agent conservateur: Without preservative

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Prior to reconstitution store at 2-8 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur IL17 Receptor B

Antigène: IL17 Receptor B (IL17RB) (Interleukin 17 Receptor B (IL17RB))

Autre désignation: IL17RB / IL17BR

Sujet: Recently, a number of cytokines belonging to the interleukin IL17 family have been identified. These are termed as IL17B, IL17C and IL17E. IL17 is a potent proinflammatory cytokine that plays roles in a number of diseases including rheumatoid arthritis, multiple sclerosis, and promotion of tumor growth. IL17B, C, and E like IL17 are able to induce proinflammatory responses. However, they do not bind to the IL17 receptor suggesting that additional IL17R related receptor might exist. Receptor for IL17B and IL17E have been independently isolated and have been designated as EV127 (in mouse) and IL17RH1 (in human), respectively. IL17E induces activation of NFkB pathway and like IL17 also induces production of IL8. IL17RH1 mRNA is highly expressed in Kidney and liver and at moderate level in small intestine, colon, and brain.Synonyms: Cytokine receptor CRL4, EVI27, IL-17 receptor B, IL-17 receptor homolog 1, IL-17RB, Interleukin-17 receptor B, Interleukin-17B receptor

ID gène: 50905

NCBI Accession: NP_062529

UniProt: Q9JIP3