JAM2 anticorps (Extracellular Domain)

N° du produit ABIN360922

Cet anticorps Rat Monoclonal détecte spécifiquement JAM2 dans WB. Il présente une réactivité envers Souris.

Aperçu rapide pour JAM2 anticorps (Extracellular Domain) (ABIN360922)

Antigène: JAM2 (Junctional Adhesion Molecule 2 (JAM2))

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp JAM2 est non-conjugé

Application: Western Blotting (WB)

Clone: 2K15

Détail du produit anti-JAM2 anticorps

Épitope: Extracellular Domain

Specificité: This antibody detects Mouse JAM-B in Western blotting. Other species not tested.

Purification: Purified

Immunogène: Recombinant protein of JAM-A extracellular domain

Isotype: IgG1

Information d'application

Indications d'application: Western Blot: 1/500 - 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Reconstitution: Restore with 0.2 mL sterile PBS and the final concentration is 0.5 mg/mL.

Buffer: 0.2 μm filtered PBS, None

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Prior to reconstitution store at 2-8 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur JAM2

Antigène: JAM2 (Junctional Adhesion Molecule 2 (JAM2))

Autre désignation: CD322 / JAM2

Sujet: Members of the junctional adhesion molecule (JAM) family are type I transmembrane glycoproteins of the immunoglobulin (Ig) superfamily that are localized in the tight junctions between endothelial or epithelial cells and appear to be involved in leukocyte transmigration. JAM-A, also known as platelet adhesion molecule 1 (PAM-1) and platelet F11 receptor, contains two V-type Ig-like domains, forms homodimers, and interacts with LFA-1. JAM-B (vasculoendothelial or VE-JAM) and JAM-C each contain two Ig domains (one V-type and one C2-type), a cytoplasmic PDZ-binding motif and a PKC phosphorylation site. JAM-C interacts with MAC-1 and facilitates JAM-B interaction with integrin alpha 4 beta 1. Junctional adhesion molecule 2 (JAM2), also know as JAMB, is a member of the newly reported glycoprotein family of adhesion molecules found at intercellular junctions of endothelial cells and lymphocytes (human). In adult murine tissue JAM2 expression is restricted to high endothelial venules of lymphoid organs, lymphoendothelial cells and endothelial cells in kidney.Synonyms: C21orf43, JAM-B, Junctional adhesion molecule 2, Junctional adhesion molecule B, VEJAM, Vascular endothelial junction-associated molecule

ID gène: 67374

NCBI Accession: NP_076333

UniProt: Q9JI59