Thymic Stromal Lymphopoietin anticorps

N° du produit ABIN360946

Cet anticorps Rat Monoclonal détecte spécifiquement Thymic Stromal Lymphopoietin dans WB. Il présente une réactivité avec des échantillons de Souris.

Aperçu rapide pour Thymic Stromal Lymphopoietin anticorps (ABIN360946)

Antigène: Thymic Stromal Lymphopoietin (TSLP)

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp Thymic Stromal Lymphopoietin est non-conjugé

Application: Western Blotting (WB)

Clone: 5G29

Détail du produit anti-Thymic Stromal Lymphopoietin anticorps

Specificité: This antibody detects Mouse TSLP. Other species not tested.

Purification: Protein A/G Affinity Chromatography

Immunogène: Purified Mouse Recombinant TSLP

Isotype: IgG2

Information d'application

Indications d'application: Western Blot: 1/500 - 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Reconstitution: Restore with 200 μL sterile PBS and the final concentration is 500 μg/mL.

Buffer: PBS, None

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Prior to reconstitution store at 2-8 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur Thymic Stromal Lymphopoietin

Antigène: Thymic Stromal Lymphopoietin (TSLP)

Autre désignation: TSLP

Sujet: Thymic Stromal Lymphopoietin (TSLP) was originally identified as an activity from the conditioned medium of a mouse thymic stromal cell line that promoted the development of B cells. The activities of mouse TSLP overlap with, but are distinct from, those of mouse IL-7. Both mouse TSLP and IL-7 can co-stimulate growth of thymocytes and mature T cells, and support B lymphopoiesis in long-term cultures of fetal liver cells and bone-marrow cells. Whereas mouse IL-7 facilitates the development of B220+/IgM- pre-B cells, mouse TSLP promotes the development B220+/IgM+ B cells. Human TSLP was reported to preferentially stimulate myeloid cells, inducing the release of T cell-attracting chemokines from monocytes and enhancing the maturation of CD11c+ dendritic cells. Human TSLP cDNA encodes a 159 amino acid (aa) residue precursor protein with a 28 aa signal sequence. Within the mature region, six of the seven cysteine residues present in the mouse TSLP involved in intramolecular disulfide bond formation are conserved in the human TSLP. Human TSLP shares approximately 43 % aa sequence identity with mouse TSLP.Synonyms: Thymic stroma-derived lymphopoietin, Thymic stromal lymphopoietin

ID gène: 53603

NCBI Accession: NP_067342

UniProt: Q9JIE6