PLAUR anticorps

N° du produit ABIN360948

Cet anticorps anti-PLAUR Monoclonal Rat (Clone 7J34) (ABIN360948) détecte spécifiquement PLAUR dans WB. L’anticorps est réactif avec des échantillons de Souris.

Aperçu rapide pour PLAUR anticorps (ABIN360948)

Antigène: PLAUR (Plasminogen Activator, Urokinase Receptor (PLAUR))

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp PLAUR est non-conjugé

Application: Western Blotting (WB)

Clone: 7J34

Détail du produit anti-PLAUR anticorps

Specificité: This antibody detects uPAR.

Purification: Protein A/G Affinity Chromatography

Immunogène: Purified Mouse Recombinant uPAR

Isotype: IgG2

Information d'application

Indications d'application: Western Blot: 1/500 - 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Reconstitution: Restore with 200 μL sterile PBS and the final concentration is 500 μg/mL.

Buffer: PBS, None

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Prior to reconstitution store at 2-8 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur PLAUR

Antigène: PLAUR (Plasminogen Activator, Urokinase Receptor (PLAUR))

Autre désignation: CD87 / uPAR

Sujet: UPAR (Urokinase plasminogen activator receptor) is a glycoprotein I anchored surface receptor specific for urokinase plasminogen activator (uPA). Upon binding to uPAR, uPA converts the surface bound, large serum beta globulin plasminogen to plasmin. Plasmin, which is also designated fibrinolysin, is a trypsin like enzyme that acts on Arg-Lys bonds and induces pericellular proteolysis in fibrin and fibrinogen, and thereby contributes to the systematic activation of the coagulation cascade. uPA and uPAR are known to be overexpressed in mesenchymal and epithelial tumor cells and are required for tumor invasion and metastasis.Synonyms: MO3, Monocyte activation antigen Mo3, PLAUR, U-PAR, Urokinase plasminogen activator surface receptor

ID gène: 18793

NCBI Accession: NP_035243

UniProt: P35456

Pathways: Inositol Metabolic Process