Thymidine Glycol anticorps

N° du produit ABIN361277

L’anticorps anti-Thymidine Glycol Monoclonal Souris est utilisé pour la détection de Thymidine Glycol dans des échantillons de Chemical. Il a été validé pour IHC.

Aperçu rapide pour Thymidine Glycol anticorps (ABIN361277)

Antigène: Thymidine Glycol (TG)

Reactivité: Chemical

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Thymidine Glycol est non-conjugé

Application: Immunohistochemistry (IHC)

Clone: 2E8

Détail du produit anti-Thymidine Glycol anticorps

Specificité: Specific to DNA containing thymidine glycol. Cross reactivity is checked to oxidized dC polymer, oxidized dG polymer and oxidized dA polymer.

Immunogène: Thymidine glycol polymer

Isotype: IgG1 kappa

Information d'application

Indications d'application: Tested for IHC. User should determine optimum titer for each application.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Concentration: 100ug/ml

Buffer: 100?g/mL IgG in 10 mM Phosphate buffered saline, pH7.4 containing 1.0 % BSA

Stock: -20 °C

Détails sur Thymidine Glycol

Antigène: Thymidine Glycol (TG)

Classe de substances: Chemical

Sujet: Thymidineglycol (TG) is one of the major oxidation products of DNA. Thymidine (T) can be damaged by oxidative stress such as radiation and energy metabolism. Two different pathways to form TG have been suggested. Deoxythymidine in DNA is directly oxidised by hydroxy radical, to form TG. TG can be also formed through an intermediate thymidine chlorohydrin, which is derived from hypochlorous acid (HOCl) from neutrophil myeloperoxidase. Thymidineglycol is derived from DNA, not from RNA. TG is the oxidative stress marker secific for DNA damage.