NEFL anticorps

N° du produit ABIN361353

Détail du produit anti-NEFL anticorps

Antigène: NEFL (Neurofilament, Light Polypeptide (NEFL))

Reactivité: Boeuf (Vache)

Hôte: Poulet

Clonalité: Polyclonal

Conjugué: Cet anticorp NEFL est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Specificité: Specific for the ~68k Neurofilament L protein in Western blots and works well on frozen sections, cells in tissue culture and on mildly formalin fixed histological sections.

Réactivité croisée: Poulet, Boeuf (Vache), Humain, Souris, Rat (Rattus)

Purification: Total IgY fraction

Immunogène: Preparation of bovine spinal cord NF-L

Information d'application

Indications d'application: Recommended Dilution: WB: 1:10,000 IF: 1:5,000 Quality Control: Western blots performed on each lot.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: total IgY fraction in PBS + 10 mM Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Détails sur NEFL

Antigène: NEFL (Neurofilament, Light Polypeptide (NEFL))

Autre désignation: NEFL (NEFL Produits)

Synonymes: anticorps NEFL, anticorps nefl, anticorps zgc:136626, anticorps AI847934, anticorps CMT2E, anticorps NF-L, anticorps NF68, anticorps Nfl, anticorps CMT1F, anticorps NFL, anticorps XNF-L, anticorps neurofilament light, anticorps neurofilament, light polypeptide, anticorps neurofilament, light polypeptide b, anticorps neurofilament, light L homeolog, anticorps NEFL, anticorps neflb, anticorps Nefl, anticorps nefl.L

Sujet: Neurofilaments are the 10nm or intermediate filament proteins found specifically in neurons, and are composed predominantly of three major proteins called NF-L, NF-M and NF-H (1). NF-L is the neurofilament light or low molecular weight polypeptide and runs on SDS-PAGE gels at about 68kDa. Antibodies to NF-L are useful for identifying neuronal cells and their processes in tissue sections and in tissue culture. Mutations in the protein coding region of the human NF-L gene cause some forms of Charcot-Marie-Tooth disease (2). Anti-Neurofilament L Western blot of rat cortex lysate showing specific immunolableing of the ~ 68k NF-L protein.

Poids moléculaire: '68 kDa

ID gène: 4747

UniProt: P02548