NEFM anticorps (C-Term)

N° du produit ABIN361354

Cet anticorps Souris Monoclonal détecte spécifiquement NEFM dans WB et IF. Il présente une réactivité envers Rat.

Aperçu rapide pour NEFM anticorps (C-Term) (ABIN361354)

Antigène: NEFM (Neurofilament Triplet M Protein (NEFM))

Reactivité: Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp NEFM est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Clone: 3H11

Détail du produit anti-NEFM anticorps

Épitope: C-Term

Specificité: Specific for the ~145k Neurofilament M protein.

Réactivité croisée: Poulet, Boeuf (Vache), Humain, Souris, Rat (Rattus)

Purification: Protein G purified culture supernatant

Immunogène: Preparation containing the extreme C-terminus expressed in and purified from E. Coli

Isotype: IgG1

Information d'application

Indications d'application: Recommended Dilution: WB: 1:1,000 IF: 1:100 Quality Control: Western blots performed on each lot.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: total IgG fraction + 10 mM Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Détails sur NEFM

Antigène: NEFM (Neurofilament Triplet M Protein (NEFM))

Autre désignation: NEFM

Sujet: Neurofilaments are the 10nm or intermediate filament proteins found specifically in neurons, and are composed predominantly of three major proteins called NF-L, NF-M and NF-H (1). NF-M is the neurofilament middle or medium molecular weight polypeptide and runs on SDS-PAGE gels at 145-160 kDa, with some variability across species boundaries. Antibodies to NF-M are useful for identifying neuronal cells and their processes in tissue sections and in tissue culture. NF-M antibodies can also be useful to visualize neurofilament accumulations seen in many neurological diseases, such as Amyotrophic Lateral Sclerosis (Lou Gehrig's disease) and Alzheimer's disease (2). Anti-Neurofilament M Western blot of rat cortex lysate showing specific immunolableing of the ~ 145k NF-M protein.

Poids moléculaire: '145 kDa

ID gène: 24588

UniProt: P12839

Pathways: Brown Fat Cell Differentiation