NEFM
Reactivité: Humain, Rat, Souris
IF
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
Recommended Dilution: WB: 1:5,000 IF: 1:1000 Quality Control: Western blots performed on each lot.
Restrictions
For Research Use only
Format
Liquid
Buffer
total IgY fraction in PBS + 10 mM Sodium azide.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
-20 °C
Glass, Kelm-Nelson, Szot, Lake, Connor, Ciucci: "Functional characterization of extrinsic tongue muscles in the Pink1-/- rat model of Parkinson disease." dans: PloS one, Vol. 15, Issue 10, pp. e0240366, (2020) (PubMed).
anticorps NEF3, anticorps NF-M, anticorps NFM, anticorps Nef3, anticorps Nfm, anticorps NF160, anticorps NF165, anticorps nef-m, anticorps nef3, anticorps nefm, anticorps nf-m, anticorps zgc:112359, anticorps nefm-a, anticorps nefm-b, anticorps neurofilament medium, anticorps neurofilament triplet M protein, anticorps neurofilament, medium polypeptide, anticorps neurofilament medium polypeptide, anticorps neurofilament medium L homeolog, anticorps neurofilament, medium polypeptide a, anticorps neurofilament medium S homeolog, anticorps NEFM, anticorps Nefm, anticorps TVAG_582010, anticorps TVAG_379630, anticorps nefm.L, anticorps nefma, anticorps nefm.S
Sujet
Neurofilaments are the 10nm or intermediate filament proteins found specifically in neurons, and are composed predominantly of three major proteins called NF-L, NF-M and NF-H (1). NF-M is the neurofilament middle or medium molecular weight polypeptide and runs on SDS-PAGE gels at 145-160 kDa, with some variability across species boundaries. Antibodies to NF-M are useful for identifying neuronal cells and their processes in tissue sections and in tissue culture. NF-M antibodies can also be useful to visualize neurofilament accumulations seen in many neurological diseases, such as Amyotrophic Lateral Sclerosis (Lou Gehrig's disease) and Alzheimer's disease (2). Anti-Neurofilament M Western blot of rat cortex lysate showing specific immunolableing of the ~ 145k NF-M protein.