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NEFM anticorps (C-Term)

NEFM Reactivité: Rat WB, IF Hôte: Poulet Polyclonal unconjugated
N° du produit ABIN361355
  • Antigène Voir toutes NEFM Anticorps
    NEFM (Neurofilament Triplet M Protein (NEFM))
    Épitope
    • 18
    • 16
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivité
    • 59
    • 48
    • 39
    • 8
    • 6
    • 6
    • 6
    • 6
    • 5
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    Rat
    Hôte
    • 40
    • 25
    • 11
    • 1
    Poulet
    Clonalité
    • 43
    • 34
    Polyclonal
    Conjugué
    • 55
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp NEFM est non-conjugé
    Application
    • 69
    • 24
    • 21
    • 18
    • 16
    • 13
    • 13
    • 13
    • 12
    • 11
    • 5
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    Specificité
    Specific for the ~145k Neurofilament M protein.
     Réactivité croisée
    Poulet, Boeuf (Vache), Humain, Souris, Rat (Rattus)
    Purification
    Total IgY fraction
    Immunogène
    Preparation containing the extreme C-terminus expressed in and purified from E. Coli
    Top Product
    Discover our top product NEFM Anticorps primaire
  • Indications d'application
    Recommended Dilution: WB: 1:5,000 IF: 1:1000 Quality Control: Western blots performed on each lot.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    total IgY fraction in PBS + 10 mM Sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
  • Glass, Kelm-Nelson, Szot, Lake, Connor, Ciucci: "Functional characterization of extrinsic tongue muscles in the Pink1-/- rat model of Parkinson disease." dans: PloS one, Vol. 15, Issue 10, pp. e0240366, (2020) (PubMed).

  • Antigène
    NEFM (Neurofilament Triplet M Protein (NEFM))
    Autre désignation
    NEFM (NEFM Produits)
    Synonymes
    anticorps NEF3, anticorps NF-M, anticorps NFM, anticorps Nef3, anticorps Nfm, anticorps NF160, anticorps NF165, anticorps nef-m, anticorps nef3, anticorps nefm, anticorps nf-m, anticorps zgc:112359, anticorps nefm-a, anticorps nefm-b, anticorps neurofilament medium, anticorps neurofilament triplet M protein, anticorps neurofilament, medium polypeptide, anticorps neurofilament medium polypeptide, anticorps neurofilament medium L homeolog, anticorps neurofilament, medium polypeptide a, anticorps neurofilament medium S homeolog, anticorps NEFM, anticorps Nefm, anticorps TVAG_582010, anticorps TVAG_379630, anticorps nefm.L, anticorps nefma, anticorps nefm.S
    Sujet
    Neurofilaments are the 10nm or intermediate filament proteins found specifically in neurons, and are composed predominantly of three major proteins called NF-L, NF-M and NF-H (1). NF-M is the neurofilament middle or medium molecular weight polypeptide and runs on SDS-PAGE gels at 145-160 kDa, with some variability across species boundaries. Antibodies to NF-M are useful for identifying neuronal cells and their processes in tissue sections and in tissue culture. NF-M antibodies can also be useful to visualize neurofilament accumulations seen in many neurological diseases, such as Amyotrophic Lateral Sclerosis (Lou Gehrig's disease) and Alzheimer's disease (2). Anti-Neurofilament M Western blot of rat cortex lysate showing specific immunolableing of the ~ 145k NF-M protein.
    Poids moléculaire
    '145 kDa
    ID gène
    24588
    UniProt
    P12839
    Pathways
    Brown Fat Cell Differentiation
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