Periostin anticorps

N° du produit ABIN361362

Cet anticorps anti-Periostin est un anticorps Lapin Polyclonal détectant Periostin dans WB et IHC. Adapté pour Souris.

Aperçu rapide pour Periostin anticorps (ABIN361362)

Antigène: Periostin (POSTN)

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Periostin est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-Periostin anticorps

Specificité: The antibody has been directly tested for reactivity in chicken, human, mouse and rat. Based on the homology of the immunogen with other species, we expect that this antibody will recognize periostin in most, if not all, species of mammals, birds, amphibians, and fishes. Specific for three periostin bands around ~93 kDa in mouse lung extract. The immunogenic peptide is present in all known splice variants of periostin and therefore this antibody recognizes all known molecular forms of periostin. The antibody also works well for immunohistochemistry on paraformaldehyde-fixed sections with a simple antigenretrieval protocol (incubate slides for 20 minutes at 90° C in 10 mM sodium citrate (pH 6.0)/ 0.1 % Tween-20).

Réactivité croisée: Poulet, Humain, Souris

Homologie: most mammalian, avian, amphibian and fishes

Purification: Antigen Affinity Purified

Immunogène: Synthetic peptide corresponding to amino acid residues from the fasciclin domain 1 of mouse periostin

Information d'application

Indications d'application: Recommended Dilution: WB: 1:1,000 IHC: 1:100 Quality Control: Western blots performed on each lot.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: ~ 0.5 mg/ml

Buffer: 100 μL in PBS

Stock: -20 °C

Détails sur Periostin

Antigène: Periostin (POSTN)

Autre désignation: POSTN

Sujet: Periostin is a matricellular protein, i.e. an extracellular matrix protein that interacts both with other ECM proteins and with cell-surface receptors. Like many other matricellular proteins, the function of periostin is important both in embryonic development and in the remodeling of adult tissues in response to pathological insults. Periostin was originally isolated as an osteoblast-specific marker that functions as a cell adhesion molecule for preosteoblasts and is thought to be involved in osteoblast recruitment, attachment and spreading (Kruzynska-Frejtag A. et al., 2004). Periostin has recently been shown to promote collagen fibrogenesis, inhibit differentiation of progenitor cells into cardiomyocytes and to be essential in maintaining the biomechanical properties of the adult myocardium (Norris et al., 2008).

Poids moléculaire: '93 kDa

ID gène: 50706

UniProt: Q62009