Vimentin anticorps
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- Antigène Voir toutes Vimentin (VIM) Anticorps
- Vimentin (VIM)
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Reactivité
- Humain
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Hôte
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Poulet
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp Vimentin est non-conjugé
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Application
- Western Blotting (WB), Immunofluorescence (IF)
- Specificité
- Specific for the ~50kDa Vimentin protein. It is expected that it will work on other mammalian tissues.
- Réactivité croisée
- Boeuf (Vache), Humain, Souris, Rat (Rattus)
- Purification
- Total IgY fraction
- Immunogène
- Recombinant human vimentin purified from E. coli
- Top Product
- Discover our top product VIM Anticorps primaire
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- Indications d'application
- Recommended Dilution: WB: 1:1,000 IF: 1:500 Quality Control: Western blots performed on each lot.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- total IgY fraction in PBS + 10 mM Sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
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Epithelial-mesenchymal transition increases tumor sensitivity to COX-2 inhibition by apricoxib." dans: Carcinogenesis, Vol. 33, Issue 9, pp. 1639-46, (2012) (PubMed).
: "Apricoxib, a novel inhibitor of COX-2, markedly improves standard therapy response in molecularly defined models of pancreatic cancer." dans: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 18, Issue 18, pp. 5031-42, (2012) (PubMed).
: "
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Epithelial-mesenchymal transition increases tumor sensitivity to COX-2 inhibition by apricoxib." dans: Carcinogenesis, Vol. 33, Issue 9, pp. 1639-46, (2012) (PubMed).
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- Antigène
- Vimentin (VIM)
- Autre désignation
- VIM (VIM Produits)
- Synonymes
- anticorps CTRCT30, anticorps cb28, anticorps vime, anticorps vim, anticorps vim1, anticorps vim2, anticorps VIM, anticorps Vimentin, anticorps vim4, anticorps vimentin, anticorps vimentin L homeolog, anticorps vimentin S homeolog, anticorps VIM, anticorps Vim, anticorps vim, anticorps vim.L, anticorps vim.S
- Sujet
- Vimentin is the major protein subunit of the 10nm or intermediate filaments (IFs) found in many kinds of mesenchymal and epithelial cells as well as developing neuronal and astrocytic precursor cells in the CNS. Vimentin is thought to be critically involved in lymphocyte adhesion and transmigration (Nieminen M et al. 2006). Copolymers are frequently formed between vimentin and other IFs, such as GFAP (in many kinds of astrocytes), desmin (in muscle cells) and neurofilament proteins (in developing neurons). Antibodies to vimentin are useful in studies of stem cells and generally to reveal the filamentous cytoskeleton. Recent studies suggest that vimentin affects prostate cancer cells motility and invasiveness (Zhao et al. 2008).
- Poids moléculaire
- '50 kDa
- ID gène
- 7431
- UniProt
- P08670
- Pathways
- Caspase Cascade in Apoptosis
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