THRB anticorps (N-Term)

N° du produit ABIN361385

L’anticorps Souris Monoclonal anti-THRB a été validé pour WB. Il convient pour détecter THRB dans des échantillons de Humain.

Aperçu rapide pour THRB anticorps (N-Term) (ABIN361385)

Antigène: THRB (Thyroid Hormone Receptor, beta (THRB))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp THRB est non-conjugé

Application: Western Blotting (WB)

Clone: 2386

Détail du produit anti-THRB anticorps

Épitope: N-Term

Specificité: Specific for the ~55k TR-ß protein.

Réactivité croisée: Humain

Purification: Protein G purified culture supernatant

Immunogène: Synthetic peptide corresponding to amino acid residues from the N-terminal region conjugated to KLH

Isotype: IgG1

Information d'application

Indications d'application: Recommended Dilution: WB: 1:1000 Quality Control: Western blots performed on each lot.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 100 μL in 10 mM HEPES (  pH 7.5), 150 mM NaCl, 100 μg per ml BSA and 50 % glycerol.

Stock: -20 °C

Détails sur THRB

Antigène: THRB (Thyroid Hormone Receptor, beta (THRB))

Autre désignation: THRB

Sujet: Thyroid hormones are essential for development of the central nervous system and deficits in these hormones during development affects such cognitive functions as learning and memory (Ambrogini et al., 2005, Chan and Kilby, 2000). Thyroid hormones exert their physiological role mainly through binding to specific nuclear receptors including the predominant isoforms of thyroid hormone receptors TRa1, TRa2, TR 1 and TR 2. TRa1, TR 1 and TR 2 bind T3 with high affinity and also bind to thyroid hormone response elements (TREs) on chromatin to regulate the transcriptional processes in several target tissues, including adult rat brain (Constantinou et al., 2005). Anti-Thyroid Hormone Receptor, -Isotype Western blot of hippocampal lysate showing specific immunolabeling of the ~58k TR- protein.

Poids moléculaire: '55 kDa

ID gène: 7068

UniProt: P10828

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Sensory Perception of Sound