THRB anticorps (N-Term)

N° du produit ABIN361385

Détail du produit anti-THRB anticorps

Antigène: THRB (Thyroid Hormone Receptor, beta (THRB))

Épitope: N-Term

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp THRB est non-conjugé

Application: Western Blotting (WB)

Specificité: Specific for the ~55k TR-ß protein.

Réactivité croisée: Humain

Purification: Protein G purified culture supernatant

Immunogène: Synthetic peptide corresponding to amino acid residues from the N-terminal region conjugated to KLH

Clone: 2386

Isotype: IgG1

Information d'application

Indications d'application: Recommended Dilution: WB: 1:1000 Quality Control: Western blots performed on each lot.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 100 μL in 10 mM HEPES (  pH 7.5), 150 mM NaCl, 100 μg per ml BSA and 50 % glycerol.

Stock: -20 °C

Détails sur THRB

Antigène: THRB (Thyroid Hormone Receptor, beta (THRB))

Autre désignation: THRB (THRB Produits)

Synonymes: anticorps C-ERBA-2, anticorps C-ERBA-BETA, anticorps ERBA2, anticorps GRTH, anticorps NR1A2, anticorps PRTH, anticorps THR1, anticorps THRB1, anticorps THRB2, anticorps Nr1a2, anticorps T3R[b], anticorps T3Rbeta, anticorps Thrb1, anticorps Thrb2, anticorps c-erbAbeta, anticorps TR-beta, anticorps TR[b]1, anticorps fj24f03, anticorps trb, anticorps wu:fj24f03, anticorps CTR BETA 2, anticorps TR-BETA, anticorps LOC734147, anticorps thrb, anticorps THRB, anticorps C-erba-beta, anticorps RATT3REC, anticorps T3rec, anticorps TRbeta, anticorps THR, anticorps TRbeta1, anticorps thyroid hormone receptor beta, anticorps thyroid hormone receptor, beta, anticorps thyroid hormone receptor, beta S homeolog, anticorps thyroid hormone receptor, beta L homeolog, anticorps THRB, anticorps Thrb, anticorps thrb, anticorps thrb.S, anticorps thrb.L

Sujet: Thyroid hormones are essential for development of the central nervous system and deficits in these hormones during development affects such cognitive functions as learning and memory (Ambrogini et al., 2005, Chan and Kilby, 2000). Thyroid hormones exert their physiological role mainly through binding to specific nuclear receptors including the predominant isoforms of thyroid hormone receptors TRa1, TRa2, TR 1 and TR 2. TRa1, TR 1 and TR 2 bind T3 with high affinity and also bind to thyroid hormone response elements (TREs) on chromatin to regulate the transcriptional processes in several target tissues, including adult rat brain (Constantinou et al., 2005). Anti-Thyroid Hormone Receptor, -Isotype Western blot of hippocampal lysate showing specific immunolabeling of the ~58k TR- protein.

Poids moléculaire: '55 kDa

ID gène: 7068

UniProt: P10828

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Sensory Perception of Sound