Glutamate Receptor 1 anticorps (pSer831)

N° du produit ABIN361476

Cet anticorps anti-Glutamate Receptor 1 est un anticorps Lapin Polyclonal détectant Glutamate Receptor 1 dans WB et ELISA. Adapté pour Rat. Ce Primary Antibody a été cité dans 9+ publications.

Aperçu rapide pour Glutamate Receptor 1 anticorps (pSer831) (ABIN361476)

Antigène: Glutamate Receptor 1 (GLUR1)

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Glutamate Receptor 1 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-Glutamate Receptor 1 anticorps

Épitope: pSer831

Specificité: Specific for endogenous levels of the ~100 kDa GluR1 protein phosphorylated at Ser831. Immunolabeling is completely eliminated by treatment with λ-phosphatase.

Réactivité croisée: Humain, Souris, Rat

Réactivité croisée (Details): The antibody has been directly tested for reactivity in Western blots with rat tissue. It is anticipated that the antibody will react with canine, chicken, human and mouse based on the fact that these species have 100% homology with the amino acid sequence used as antigen.

Homologie: canine, chicken, human

Attributs du produit: Our GluR1-Subunit (Ser831) rabbit polyclonal phosphospecific primary antibody is produced in-house. It detects GluR1-Subunit (Ser831) and is antigen affinity purified from pooled serum. It is great for use in ELISA, WB.

Purification: Prepared from pooled rabbit serum by affinity purification via sequential chromatography on phospho and non-phosphopeptide affinity columns.

Immunogène: Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser831 of rat GluR1 conjugated to keyhole limpet hemocyanin (KLH).

Isotype: IgG

Information d'application

Indications d'application:

Dilution Range: WB Brain: 1:1000

Dilution Range: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg per ml BSA and 50 % glycerol.

Conseil sur la manipulation: Avoid repeated freezing and thawing

Stock: -20 °C

Stockage commentaire: Storage at -20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20°C.

Date de péremption: 12 months

Références pour anticorps anti-Glutamate Receptor 1 (ABIN361476)

Mao, Wang: "Upregulation of AMPA receptor GluA1 phosphorylation by blocking adenosine A1 receptors in the male rat forebrain." dans: Brain and behavior, Vol. 10, Issue 3, pp. e01543, (2020) (PubMed).

Xue, Chen, He, Jin, Mao, Wang: "Integrated regulation of AMPA glutamate receptor phosphorylation in the striatum by dopamine and acetylcholine." dans: Neuropharmacology, (2016) (PubMed).

Pasek, Wang, Colbran: "Differential CaMKII regulation by voltage-gated calcium channels in the striatum." dans: Molecular and cellular neurosciences, Vol. 68, pp. 234-43, (2016) (PubMed).

Mao, Xue, Jin, Wang: "Dynamic increases in AMPA receptor phosphorylation in the rat hippocampus in response to amphetamine." dans: Journal of neurochemistry, Vol. 133, Issue 6, pp. 795-805, (2015) (PubMed).

Mao, Hastings, Fibuch, Wang: "Propofol selectively alters GluA1 AMPA receptor phosphorylation in the hippocampus but not prefrontal cortex in young and aged mice." dans: European journal of pharmacology, Vol. 738, pp. 237-44, (2014) (PubMed).

Xue, Edwards, Mao, Guo, Jin, Fibuch, Wang: "Rapid and sustained GluA1 S845 phosphorylation in synaptic and extrasynaptic locations in the rat forebrain following amphetamine administration." dans: Neurochemistry international, Vol. 64, pp. 48-54, (2013) (PubMed).

Ferrario, Loweth, Milovanovic, Wang, Wolf: "Distribution of AMPA receptor subunits and TARPs in synaptic and extrasynaptic membranes of the adult rat nucleus accumbens." dans: Neuroscience letters, Vol. 490, Issue 3, pp. 180-4, (2011) (PubMed).

Jiao, Jalan-Sakrikar, Robison, Baucum, Bass, Colbran: "Characterization of a central Ca2+/calmodulin-dependent protein kinase IIalpha/beta binding domain in densin that selectively modulates glutamate receptor subunit phosphorylation." dans: The Journal of biological chemistry, Vol. 286, Issue 28, pp. 24806-18, (2011) (PubMed).

Sears, Liu, Narayanan, Sharf, Yeckel, Laubach, Aghajanian, DiLeone: "Regulation of nucleus accumbens activity by the hypothalamic neuropeptide melanin-concentrating hormone." dans: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 30, Issue 24, pp. 8263-73, (2010) (PubMed).

Détails sur Glutamate Receptor 1

Antigène: Glutamate Receptor 1 (GLUR1)

Autre désignation: GRIA1

Sujet:

Synonyms: GLUR 1 antibody, GLUR A antibody, AMPA 1 antibody, AMPA selective glutamate receptor 1 antibody, AMPA-selective glutamate receptor 1 antibody, GluA1 antibody, GLUH1 antibody, GluR K1 antibody, GluR-1 antibody, GluR-A antibody, GluR-K1 antibody, GLUR1 antibody, GLURA antibody, GluRK1 antibody, Glutamate receptor 1 antibody, Glutamate receptor ionotropic AMPA 1 antibody, Glutamate receptor ionotropic antibody, Glutamate receptor, ionotropic, AMPA 1 antibody, Gria1 antibody, GRIA1_HUMAN antibody, HBGR1 antibody, MGC133252 antibody, OTTHUMP00000160643 antibody, OTTHUMP00000165781 antibody, THUMP00000224241 antibody, OTTHUMP00000224242 antibody, OTTHUMP00000224243 antibody

Description Logic: Our GluR1-Subunit (Ser831) rabbit polyclonal phosphospecific primary antibody is produced . It detects GluR1-Subunit (Ser831) and is antigen affinity purified from pooled serum. It is great for use in ELISA, WB.

Gene Name Alternatives: GRIA1

Poids moléculaire: 100 kDa

ID gène: 50592

NCBI Accession: NP_113796

UniProt: P19490

Pathways: Signalisation PI3K-Akt