Cité dans 1 publication.
Cet anticorps anti-JunB est un anticorps Polyclonal produit chez le Lapin, détectant JunB dans IHC et IF. Convient pour Humain, Souris et Rat.
The antibody detects endogenous level of JunB only when phosphorylated at serine 79.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed bychromatography using non-phosphopeptide corresponding to the phosphorylation site.
Immunogène
Peptide sequence around phosphorylation site of pSer79 (G-A-S (p) -L-K) derived from Human JunB. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.
Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C/-20 °C
Stockage commentaire
Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
Vartanian, Masri, Martin, Cloninger, Holmes, Artinian, Funk, Ruegg, Gera: "AP-1 regulates cyclin D1 and c-MYC transcription in an AKT-dependent manner in response to mTOR inhibition: role of AIP4/Itch-mediated JUNB degradation." dans: Molecular cancer research : MCR, Vol. 9, Issue 1, pp. 115-30, (2011) (PubMed).
Antigène
JunB (JUNB)
(Jun B Proto-Oncogene (JUNB))
Autre désignation
JunB
Sujet
Transcription factor involved in regulating gene activity following the primary growth factor response. Binds to the DNA sequence 5'-TGA[CG]TCA-3'.