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ICAM1 anticorps (pTyr512)

ICAM1 Reactivité: Humain WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN362032
  • Antigène Voir toutes ICAM1 Anticorps
    ICAM1 (Intercellular Adhesion Molecule 1 (ICAM1))
    Épitope
    • 18
    • 16
    • 16
    • 8
    • 7
    • 6
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pTyr512
    Reactivité
    • 221
    • 87
    • 38
    • 7
    • 5
    • 5
    • 4
    • 3
    • 1
    • 1
    Humain
    Hôte
    • 120
    • 120
    • 32
    • 4
    • 2
    • 1
    • 1
    • 1
    Lapin
    Clonalité
    • 159
    • 119
    • 1
    Polyclonal
    Conjugué
    • 126
    • 26
    • 25
    • 21
    • 12
    • 6
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp ICAM1 est non-conjugé
    Application
    • 170
    • 159
    • 64
    • 63
    • 46
    • 40
    • 37
    • 35
    • 31
    • 28
    • 25
    • 21
    • 12
    • 10
    • 6
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Specificité
    The antibody detects endogenous level of ICAM-1 only when phosphorylated at tyrosine 512.
    Purification
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific phosphopeptide. The antibody against non-phosphopeptide was removedby chromatography using non-phosphopeptide corresponding to the phosphorylation site.
    Immunogène
    Peptide sequence around phosphorylation site of pTyr512 (K-K-Y (p) -R-L) derived from Human ICAM-1. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.
    Isotype
    IgG
    Top Product
    Discover our top product ICAM1 Anticorps primaire
  • Indications d'application
    Western blotting: 1:500-1:1000  
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
  • Antigène
    ICAM1 (Intercellular Adhesion Molecule 1 (ICAM1))
    Autre désignation
    ICAM-1 (ICAM1 Produits)
    Synonymes
    anticorps BB2, anticorps CD54, anticorps P3.58, anticorps Icam-1, anticorps Ly-47, anticorps MALA-2, anticorps ICAM, anticorps ICAM-1, anticorps ICAM1, anticorps intercellular adhesion molecule 1, anticorps intercellular adhesion molecule-1, anticorps ICAM1, anticorps Icam1, anticorps ICAM-1
    Classe de substances
    Viral Protein
    Sujet
    ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin a-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through SGEF and RHOG activation. In case of rhinovirus infection acts as a cellular receptor for the virus.
    Poids moléculaire
    92 kDa
    NCBI Accession
    NP_000192
    UniProt
    P05362
    Pathways
    Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization, Carbohydrate Homeostasis, Regulation of Leukocyte Mediated Immunity, Thromboxane A2 Receptor Signaling
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