EIF4B anticorps (pSer422)

N° du produit ABIN362448

Détail du produit anti-EIF4B anticorps

Antigène: EIF4B (Eukaryotic Translation Initiation Factor 4B (EIF4B))

Épitope: pSer422

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EIF4B est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Specificité: The antibody detects endogenous level of eIF4B only when phosphorylated at Serine 422.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific phosphopeptide. The antibody against non-phosphopeptide was removedby chromatography using non-phosphopeptide corresponding to the phosphorylation site.

Immunogène: Peptide sequence around phosphorylation site of pSer422 (T-G-S (p) -E-S) derived from Human eIF4B. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.

Isotype: IgG

Information d'application

Indications d'application: Western blotting: 1:500-1:1000
Immunohistochemistry: 1:50-1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Détails sur EIF4B

Antigène: EIF4B (Eukaryotic Translation Initiation Factor 4B (EIF4B))

Autre désignation: eIF4B (EIF4B Produits)

Synonymes: anticorps EIF-4B, anticorps PRO1843, anticorps CG10837, anticorps Dm-eIF4B, anticorps Dmel\\CG10837, anticorps Eif4B, anticorps eIF-4B-L, anticorps eIF-4B-S, anticorps eIF-4b, anticorps eIF4B, anticorps eIF4B-L, anticorps eIF4B-S, anticorps eIf4b, anticorps 2310046H11Rik, anticorps AL024095, anticorps C85189, anticorps Eif4a2, anticorps eif4b, anticorps fb15c09, anticorps wu:fb15c09, anticorps zgc:101532, anticorps MGC89384, anticorps eukaryotic translation initiation factor 4B, anticorps eukaryotic initiation factor 4B, anticorps Eukaryotic initiation factor 4B, anticorps eukaryotic translation initiation factor 4Bb, anticorps eukaryotic translation initiation factor 4Ba, anticorps eukaryotic translation initiation factor 4B S homeolog, anticorps EIF4B, anticorps Eif4B, anticorps eIF-4B, anticorps Eif4b, anticorps eif4bb, anticorps eif4b, anticorps eif4ba, anticorps eif4b.S, anticorps LOC100284982, anticorps LOC100380867

Sujet: Required for the binding of mRNA to ribosomes. Functions in close association with EIF4-F and EIF4-A. Binds near the 5'-terminal cap of mRNA in presence of EIF-4F and ATP. Promotes the ATPase activity and the ATP-dependent RNA unwinding activity of both EIF4-A and EIF4-F.

Poids moléculaire: 80 kDa

NCBI Accession: NP_001408

UniProt: P23588