Glutamate Receptor 1 anticorps (AA 847-851)
Aperçu rapide pour Glutamate Receptor 1 anticorps (AA 847-851) (ABIN362938)
Antigène
Voir toutes Glutamate Receptor 1 (GLUR1) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 847-851
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Specificité
- The antibody detects endogenous level of total GluR1 protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Immunogène
- Peptide sequence around AA 847-851 (Q-Q-S-I-N ) derived from Human GluR1. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.
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Isotype
- IgG
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Indications d'application
- Western blotting: 1:500-1:1000
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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- Glutamate Receptor 1 (GLUR1)
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Autre désignation
- GluR1
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Sujet
- Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes with multiple subunits, each possessing transmembrane regions, and all arranged to form a ligand-gated ion channel. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. This gene belongs to a family of a-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptors. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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Poids moléculaire
- 110 kDa
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NCBI Accession
- NP_000818
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UniProt
- P42261
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Pathways
- Signalisation PI3K-Akt
Antigène
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