Cet anticorps anti-EIF4B Polyclonal Lapin (ABIN363082) détecte spécifiquement EIF4B dans IHC.
L’anticorps est réactif avec des échantillons de Humain et Souris.
The antibody detects endogenous level of total eIF4B protein.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific immunogen.
Immunogène
Peptide sequence around AA 420-424 (T-G-S-E-S) derived from Human eIF4B. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.
Required for the binding of mRNA to ribosomes. Functions in close association with EIF4-F and EIF4-A. Binds near the 5'-terminal cap of mRNA in presence of EIF-4F and ATP. Promotes the ATPase activity and the ATP-dependent RNA unwinding activity of both EIF4-A and EIF4-F.