PARK7/DJ1 anticorps (C-Term)

N° du produit ABIN363457

Détail du produit anti-PARK7/DJ1 anticorps

Antigène: PARK7/DJ1 (PARK7) (Parkinson Protein 7 (PARK7))

Épitope: AA 150-189, C-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PARK7/DJ1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP), Immunocytochemistry (ICC), Functional Studies (Func)

Specificité: Reacts with humanand mouse Protein DJ-1

Réactivité croisée: Boeuf (Vache), Poulet

Réactivité croisée (Details): May cross react with rat, bovine, Zebra fish, Golden hamster and chicken proteins (100 % sequence homology).

Purification: Antiserum

Immunogène: Synthetic peptide corresponding to the C-terminus (within residues 150-189) of human Park7(DJ-1).

Information d'application

Indications d'application:

Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only :
ICC1:500 IP1:200 WB1:2 000

Restrictions: For Research Use only

Stockage

Format: Liquid

Stock: 4 °C/-20 °C

Stockage commentaire: Short term storage at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.

Date de péremption: 6 months

Détails sur PARK7/DJ1

Antigène: PARK7/DJ1 (PARK7) (Parkinson Protein 7 (PARK7))

Autre désignation: Protein DJ-1 (PARK7 Produits)

Synonymes: anticorps DJ-1, anticorps DJ1, anticorps CAP1, anticorps Dj1, anticorps SP22, anticorps dj1, anticorps zgc:103725, anticorps park7b, anticorps park7, anticorps park7a, anticorps Parkinsonism associated deglycase, anticorps Parkinson disease (autosomal recessive, early onset) 7, anticorps parkinson protein 7, anticorps parkinson protein 7 S homeolog, anticorps parkinson protein 7 L homeolog, anticorps PARK7, anticorps Park7, anticorps park7, anticorps park7.S, anticorps park7.L

Sujet: Park7/DJ-1 is one of several genes thought to cause autosomal-recessive early-onset parkinsonism. Protects cells against oxidative stress and cell death. Plays a role in regulating expression or stability of the mitochondrial uncoupling proteins SLC25A14 and SLC25A27 in dopaminergic neurons of the substantia nigra pars compacta and attenuates the oxidative stress induced by calcium entry into the neurons via L-type channels during pacemaking. Eliminates hydrogen peroxide and protects cells against hydrogen peroxide-induced cell death.

ID gène: 11315

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Proton Transport