HPV16 E7 anticorps

N° du produit ABIN363828

Cet anticorps anti-HPV16 E7 est un anticorps Souris Monoclonal détectant HPV16 E7 dans WB et ELISA. Adapté pour Human Papillomavirus (HPV).

Aperçu rapide pour HPV16 E7 anticorps (ABIN363828)

Antigène: HPV16 E7 (HPV-16 E7) (Human Papilloma Virus 16 E7 (HPV-16 E7))

Reactivité: Human Papillomavirus (HPV)

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp HPV16 E7 est non-conjugé

Application: Western Blotting (WB), ELISA

Clone: 716-F10

Détail du produit anti-HPV16 E7 anticorps

Specificité: Recognizes both the monomer and dimer forms of the E7 oncoprotein of human papilloma virus 16. Human papillomavirus (HPV) is a diverse group of DNA-based viruses that infect skin and mucous membranes of humans and animals. Some HPV types are the causative agents of cervical cancer, with types 16 and 18 being particularly high-risk. The viral proteins E6 and E7 disrupts normal cell cycle regulation by interacting with p53 (a tumor-suppressing transcription factor) and Rb (retinoblastoma protein, also a tumor-suppressor). E7 particularly binds to Rb and histone deacetylases, resulting in activation of the E2F genes, which code for a family of transcription factors. The viral proteins E6 and E7 might be of particular interest in the development of therapeutic vaccines, since they are expressed early in viral infection. Does not cross-react with E7 protein of HPV-18.

Purification: Affinity purified

Immunogène: Oncoprotein E7 from human papillomavirus 16.

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

Target Species of Antibody: Human Papillomavirus

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.2, 0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.

Détails sur HPV16 E7

Antigène: HPV16 E7 (HPV-16 E7) (Human Papilloma Virus 16 E7 (HPV-16 E7))

Autre désignation: HPV16 E7

Classe de substances: Viral Protein

Sujet: Name/Gene ID: HPV16-E7

Synonyms: HPV16-E7

ID gène: 1489079