Endoglin anticorps

N° du produit ABIN371132

L’anticorps Rat Monoclonal anti-Endoglin a été validé pour WB, FACS et IHC (fro). Il convient pour détecter Endoglin dans des échantillons de Souris.

Aperçu rapide pour Endoglin anticorps (ABIN371132)

Antigène: Endoglin (ENG)

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp Endoglin est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: MJ7-18

Détail du produit anti-Endoglin anticorps

Attributs du produit: Synonyms: ENG, END, HHT1, ORW, ORW1

Purification: Purified

Immunogène: Inflamed mouse skin. (Ref. 1)

Isotype: IgG2a

Information d'application

Indications d'application: Flow Cytometry: Identification and enumeration of CD105+ cells. (< / = 1 μg/10^6 cells). Immunohistochemistry on Frozen Sections. Western Blotting.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: 100 mM Borate Buffered Saline, pH 8.2. No preservatives or amine-containing buffer salts added.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur Endoglin

Antigène: Endoglin (ENG)

Autre désignation: CD105 / Endoglin

Sujet: CD105/endoglin is a disulfide-linked type II transmembrane homodimer that is predominantly expressed on vascular endothelial cells. It is also found on pre-erythroblasts, macrophages and lymphoid and myeloid leukemic cells. (Ref.2) Both mouse and human CD105 exhibit > 70 % sequence homology in their cytoplasmic domains with type III Transforming Growth Factor beta (TGF-beta) receptor. (Ref.3) CD105 has been shown to be one of several receptors for the various isoforms of TGF-beta, which in turn is one of a family of proteins involved in regulation of cell differentiation, migration of cells and control of the immune response. (Ref.4)Synonyms: END, ENG, HHT1, ORW, ORW1

UniProt: Q63961