Integrin beta 7 anticorps

N° du produit ABIN371135

L’anticorps anti-Integrin beta 7 Monoclonal Rat est utilisé pour la détection de Integrin beta 7 dans des échantillons de Souris. Il a été validé pour FACS, IHC (fro) et Func.

Aperçu rapide pour Integrin beta 7 anticorps (ABIN371135)

Antigène: Integrin beta 7 (ITGB7)

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp Integrin beta 7 est non-conjugé

Application: Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Functional Studies (Func)

Clone: DATK32

Détail du produit anti-Integrin beta 7 anticorps

Specificité: This antibody is specific to mouse LPAM1 (Integrin alpha 4 beta 7). It recognises a conformational epitope on the heterodimer.

Attributs du produit: Synonyms: Integrin beta-P, M290 IEL antigen, ITGB7, LPAM-1, LPAM1, Lymphocyte Peyer PatchAdhesion Molecule

Purification: Purified

Immunogène: AKR/Cum mouse spontaneous T lymphoma cell line TK1. (Ref. 1)

Isotype: IgG2a

Information d'application

Indications d'application: Flow Cytometry: < / = 1 μg/10^6 cells. (Ref.1-4)Immunohistochemistry on Frozen Sections. (Ref.3)Induction of homotypic cellular aggregation. Blockade of binding to cell adhesion molecules.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: 100 mM Borate Buffered Saline, pH 8.2. No preservatives or amine-containing buffer salts added.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur Integrin beta 7

Antigène: Integrin beta 7 (ITGB7)

Autre désignation: Integrin beta-7

Sujet: The lymphocyte Peyer's patch adhesion molecule (LPAM-1), also known as Integrin alpha 4 beta 7 is a member of the integrin family of cell surface receptors. It is expressed primarily on mucosal lymphocytes, but is also present on NK cells and eosinophils. The alpha 4 beta 7 heterodimer mediates the binding of lymphocytes to its ligand, mucosal vascular addressin (MAdCAM1) on the high endothelial venules, thereby directing the homing of lymphocytes into Peyer's patches and intestinal lamina propria. (Ref.1-4)Synonyms: Adhesion Molecule, ITGB7, Integrin beta-P, LPAM-1, LPAM1, Lymphocyte Peyer Patch, M290 IEL antigen

ID gène: 16421

UniProt: P26011

Pathways: Integrin Complex