MHC Class II I-Ab anticorps

N° du produit ABIN371141

L’anticorps anti-MHC Class II I-Ab Monoclonal Rat est utilisé pour la détection de MHC Class II I-Ab dans des échantillons de Souris. Il a été validé pour FACS et Func.

Aperçu rapide pour MHC Class II I-Ab anticorps (ABIN371141)

Antigène: MHC Class II I-Ab

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp MHC Class II I-Ab est non-conjugé

Application: Flow Cytometry (FACS), Functional Studies (Func)

Clone: NIMR-4

Détail du produit anti-MHC Class II I-Ab anticorps

Attributs du produit: Synonyms: H2-Eb1, H-2 class II histocompatibility antigen I-A beta chain

Purification: Purified

Isotype: IgG2b

Information d'application

Indications d'application: Flow Cytometry: < / = 1 μg/10^6 cells. Complement-dependent Cytotoxicity Assays.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: 100 mM Borate Buffered Saline, pH 8.2. No preservatives or amine-containing buffer salts added.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur MHC Class II I-Ab

Antigène: MHC Class II I-Ab

Sujet: MHC Class II antigens are heterodimers consisting of one alpha chain(31-34kD) and one beta chain (26-29kD). The family of monoclonal antibodies (ER-TR 3, ER-TR 2, ER-TR 1) detect MHC class II antigens encoded by the murine Ia region of the H-2 complex, corresponding to the human HLA-DR region. MHC Class II antigens are a valuable tool for studying T helper cell interaction with class II positive antigen presenting cells (dendritic cells, B cells, macrophages) and offer new possibilities for studying the development of T helper cells since these antibodies also stain stromal cells in the thymus. MHC Class II antigens are also inducible on a number of other cells (endothelium and epithelial cells) by interferon gamma.Synonyms: H-2 class II histocompatibility antigen I-A beta chain, H2-Eb1

UniProt: P18468