CD8 anticorps
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- Antigène Voir toutes CD8 Anticorps
- CD8
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Reactivité
- Poulet, Dindon
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp CD8 est non-conjugé
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Application
- Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunoprecipitation (IP), Functional Studies (Func)
- Attributs du produit
- Synonyms: T-cell surface glycoprotein CD8 alpha chain, T-cell surface glycoprotein Lyt-2
- Purification
- Purified
- Clone
- 28-02-98
- Isotype
- IgG2b
- Top Product
- Discover our top product CD8 Anticorps primaire
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- Indications d'application
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Flow Cytometry. (Ref.4)Immunoprecipitation. (Ref.4)Immunohistochemistry (Acetone-Fixed, Frozen Tissue Sections). Positive Cell Sorting: Purification of CD8+ T cells.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Concentration
- 0.5 mg/mL
- Buffer
- 100 mM Borate Buffered Saline, pH 8.2. No preservatives or amine-containing buffer salts added.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
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Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. - Date de péremption
- 12 months
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- Antigène
- CD8
- Autre désignation
- CD8 (CD8 Produits)
- Synonymes
- anticorps CD8, anticorps Leu2, anticorps MAL, anticorps p32, anticorps CD8a molecule, anticorps CD8A
- Sujet
- The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell to cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T cell receptor on the T lymphocyte recognize antigen displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. CD8 is expressed on most thymocytes and approximately 1/3 of peripheral blood T cells in humans. CD8 alpha/beta heterodimers are expressed only on TCR alpha/beta T cells, whereas CD8 alpha homodimers can be expressed on alpha/beta and gamma/delta T cells and some NK cells in humans. The pattern of expression in other species has not been well documented.Synonyms: CD8 alpha chain, CD8A, MAL, T-cell surface glycoprotein CD8 alpha chain, T-lymphocyte differentiation antigen T8/Leu-2
- UniProt
- Q0R4I4
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