CD43 anticorps (APC)

N° du produit ABIN371547

Cet anticorps anti-CD43 est un anticorps Souris Monoclonal détectant CD43 dans FACS. Adapté pour Humain.

Aperçu rapide pour CD43 anticorps (APC) (ABIN371547)

Antigène: CD43 (SPN) (Sialophorin (SPN))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD43 est conjugé à/à la APC

Application: Flow Cytometry (FACS)

Clone: DF-T1

Détail du produit anti-CD43 anticorps (APC)

Specificité: This antibody recognizes CD43.

Attributs du produit: Synonyms: Leukocyte sialoglycoprotein, Sialophorin, Galactoglycoprotein, SPN

Isotype: IgG1

Information d'application

Indications d'application: Flow Cytometry: 10 μL/10^6 cells.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: PBS containing 0.09 % Sodium Azide as preservative and a stabilizing agent.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C. DO NOT FREEZE! This product is photosensitive and should be protected from light. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur CD43

Antigène: CD43 (SPN) (Sialophorin (SPN))

Autre désignation: CD43 / Leukosialin

Sujet: CD43 is one of the major glycoproteins of thymocytes and T lymphocytes, it plays a role in the physicochemical properties of the T cell surface and in lectin binding. CD43 presents carbohydrate ligands to selectins. It has an extended rodlike structure that could protrude above the glycocalyx of the cell and allow multiple glycan chains to be accessible for binding. The antigen is a counter receptor for SN/Siglec1. During T cell activation CD43 is actively removed from the T cell antigen presenting cell contact site suggesting a negative regulatory role in adaptive immune response. CD43 is expressed by the majority of leucocytes, with the exception of most B cells. However CD43 expression is seen in some cases of B cell lymphocytic lymphoma and centrocytic lymphoma.Synonyms: Galactoglycoprotein, Leukocyte sialoglycoprotein, SPN, Sialophorin

ID gène: 6693

UniProt: P16150

Pathways: Regulation of Leukocyte Mediated Immunity