MMP3 anticorps
Aperçu rapide pour MMP3 anticorps (ABIN371657)
Antigène
Voir toutes MMP3 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Specificité
- This antibody is specific for Human MMP-3. Does not cross react to Human MMP-1, MMP-2 or MMP-9.
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Attributs du produit
- Synonyms: Stromelysin-1, SL-1, Matrix metalloproteinase-3, Transin-1, MMP3, STMY1
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Purification
- Purified
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Immunogène
- Recombinant MMP-3.
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Isotype
- IgG2a
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Indications d'application
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ELISA: 1/3,000-1/8,000. Immunohistochemistry (Frozen/Paraffin): < / = 2 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Concentration
- 0.5 mg/mL
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Buffer
- 100 mM Borate buffered saline, pH 8.2. No preservatives or amine-containing buffer salts added.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
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Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. -
Date de péremption
- 12 months
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- MMP3 (Matrix Metallopeptidase 3 (Stromelysin 1, Progelatinase) (MMP3))
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Autre désignation
- MMP-3
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Sujet
- Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. MMP3 is an enzyme which degrades fibronectin, laminin, collagens III, IV, IX, and X, and cartilage proteoglycans. The enzyme is thought to be involved in wound repair, progression of atherosclerosis, and tumor initiation. MMP3 is reported to be implicated in rheumatoid arthritis and some forms of cancer.Synonyms: MMP3, Matrix metalloproteinase-3, SL-1, STMY1, Stromelysin-1, Transin-1
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ID gène
- 4314
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UniProt
- P08254
Antigène
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