Retinoic Acid Receptor beta anticorps (N-Term)

N° du produit ABIN371838

Cet anticorps anti-Retinoic Acid Receptor beta est un anticorps Souris Monoclonal détectant Retinoic Acid Receptor beta dans WB. Adapté pour Humain, Souris, Rat, Chien et Cobaye.

Aperçu rapide pour Retinoic Acid Receptor beta anticorps (N-Term) (ABIN371838)

Antigène: Retinoic Acid Receptor beta (RARB) (Retinoic Acid Receptor, beta (RARB))

Reactivité: Humain, Souris, Rat, Chien, Cobaye

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Retinoic Acid Receptor beta est non-conjugé

Application: Western Blotting (WB)

Clone: 336

Détail du produit anti-Retinoic Acid Receptor beta anticorps

Épitope: N-Term

Specificité: This antibody is specific for the ~48k RAR-beta isotype.

Réactivité croisée (Details): Species reactivity (expected):Canine (Dog), Guinea Pig, Mouse and Rat.
Species reactivity (tested):Human.

Attributs du produit: Synonyms: RAR-epsilon, HAP, NR1B2, Retinoic acid receptor beta, HBV-activated protein, Nuclearreceptor subfamily 1 group B member 2

Purification: Prepared from Mouse Ascites by Ammonium Sulfate Precipitation followed by Affinity Chromatography on Protein G.

Immunogène: Peptide corresponding to amino acids from N-terminal region of human retinoic acidreceptor, beta-isotype. Remarks: The antigen is identical in both beta-1 and beta-2 isoforms.

Isotype: IgG1

Information d'application

Indications d'application: Western Blot: 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg/mL BSA and 50 % Glycerol.

Stock: -20 °C

Stockage commentaire: Store the antibody undiluted (in aliquots) at -20 °C. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur Retinoic Acid Receptor beta

Antigène: Retinoic Acid Receptor beta (RARB) (Retinoic Acid Receptor, beta (RARB))

Autre désignation: RAR-beta / RARB

Sujet: Retinoic acid (RA, active metabolite of vitamin A) plays a prominent role in regulating the transition of proliferating precursor cells (such as carcinoma cells and neuronal precursors) to postmitotic differentiated cells (Joshi et al., 2005). The retinoid X receptors (RXRs) family (RXR-alpha, beta and gamma), preferentially bind 9-cis-RA and regulate gene transcription by forming heterodimers with a second family of RA receptors. RAs have been suggested to potentially play a therapeutic role in cervical cancer (Abu et al., 2005). RAs are known to play key roles in neuronal development and an increasing body of evidence indicates that retinoid signaling may regulate synaptic plasticity and associated learning and memory behaviors (Lane and Bailey, 2005).Synonyms: HAP, HBV-activated protein, NR1B2, Nuclear receptor subfamily 1 group B member 2, RAR-epsilon, Retinoic acid receptor beta

ID gène: 5915

UniProt: P10826

Pathways: Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway