Retinoid X Receptor beta anticorps

N° du produit ABIN371839

Cet anticorps Souris Monoclonal détecte spécifiquement Retinoid X Receptor beta dans WB. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour Retinoid X Receptor beta anticorps (ABIN371839)

Antigène: Retinoid X Receptor beta (RXRB) (Retinoid X Receptor, beta (RXRB))

Reactivité: Humain, Souris, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Retinoid X Receptor beta est non-conjugé

Application: Western Blotting (WB)

Clone: 147

Détail du produit anti-Retinoid X Receptor beta anticorps

Specificité: This antibody is specific for the ~48k RAR-beta isotype.

Réactivité croisée (Details): Species reactivity (expected):Human.
Species reactivity (tested):Mouse and Rat

Attributs du produit: Synonyms: NR2B2, H-2RIIBP, Rcor-1, Retinoic acid receptor RXR-beta, Retinoid X receptor beta, Nuclearreceptor subfamily 2 group B member 2, Nuclear Receptor Coregulator 1

Purification: Prepared from Mouse Ascites by Ammonium Sulfate Precipitation followed by Affinity Chromatography on Protein G.

Immunogène: Hinge peptide corresponding to amino acids from Human, Mouse and Rat retinoid Xreceptor, beta-isotype.

Isotype: IgG1

Information d'application

Indications d'application: Western Blot: 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg/mL BSA and 50 % Glycerol.

Stock: -20 °C

Stockage commentaire: Store the antibody undiluted (in aliquots) at -20 °C. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur Retinoid X Receptor beta

Antigène: Retinoid X Receptor beta (RXRB) (Retinoid X Receptor, beta (RXRB))

Autre désignation: RXR-beta / RXRB

Sujet: Retinoic acid (RA, active metabolite of vitamin A) plays a prominent role in regulating the transition of proliferating precursor cells (such as carcinoma cells and neuronal precursors) to postmitotic differentiated cells (Joshi et al., 2005). The retinoid X receptors (RXRs) family (RXR-alpha, beta and gamma), preferentially bind 9-cis-RA and regulate gene transcription by forming heterodimers with a second family of RA receptors. RAs have been suggested to potentially play a therapeutic role in cervical cancer (Abu et al., 2005). RAs are known to play key roles in neuronal development and an increasing body of evidence indicates that retinoid signaling may regulate synaptic plasticity and associated learning and memory behaviors (Lane and Bailey, 2005).Synonyms: H-2RIIBP, NR2B2, Nuclear Receptor Coregulator 1, Nuclear receptor subfamily 2 group B member 2, Rcor-1, Retinoic acid receptor RXR-beta, Retinoid X receptor beta

ID gène: 6257

UniProt: P28702

Pathways: Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway