Retinoid X Receptor gamma anticorps (Hinge Region)

N° du produit ABIN371840

L’anticorps Souris Monoclonal anti-Retinoid X Receptor gamma a été validé pour WB. Il convient pour détecter Retinoid X Receptor gamma dans des échantillons de Humain, Souris, Rat, Boeuf (Vache) et Non-Human Primate.

Aperçu rapide pour Retinoid X Receptor gamma anticorps (Hinge Region) (ABIN371840)

Antigène: Retinoid X Receptor gamma (RXRG) (Retinoid X Receptor, gamma (RXRG))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Non-Human Primate

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Retinoid X Receptor gamma est non-conjugé

Application: Western Blotting (WB)

Clone: 1373

Détail du produit anti-Retinoid X Receptor gamma anticorps

Épitope: Hinge Region

Specificité: This antibody is specific for the ~48k RAR-gamma isotype.

Réactivité croisée (Details): Species reactivity (expected):Bovine, Rat, Mouse and non-Human Primates.
Species reactivity (tested):Human.

Attributs du produit: Synonyms: NR2B3, Retinoic acid receptor RXR-gamma, Retinoid X receptor gamma, Nuclear receptorsubfamily 2 group B member 3

Purification: Prepared from Mouse Ascites by Ammonium Sulfate Precipitation followed by Affinity Chromatography on Protein G.

Immunogène: Hinge peptide from Human retinoid X receptor, gamma-isotype.

Isotype: IgG1

Information d'application

Indications d'application: Western Blot: 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg/mL BSA and 50 % Glycerol.

Stock: -20 °C

Stockage commentaire: Store the antibody undiluted (in aliquots) at -20 °C. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur Retinoid X Receptor gamma

Antigène: Retinoid X Receptor gamma (RXRG) (Retinoid X Receptor, gamma (RXRG))

Autre désignation: RXR-gamma / RXRG

Sujet: Retinoic acid (RA, active metabolite of vitamin A) plays a prominent role in regulating the transition of proliferating precursor cells (such as carcinoma cells and neuronal precursors) to postmitotic differentiated cells (Joshi et al., 2005). The retinoid X receptors (RXRs) family (RXR-alpha, beta and gamma), preferentially bind 9-cis-RA and regulate gene transcription by forming heterodimers with a second family of RA receptors. RAs have been suggested to potentially play a therapeutic role in cervical cancer (Abu et al., 2005). RAs are known to play key roles in neuronal development and an increasing body of evidence indicates that retinoid signaling may regulate synaptic plasticity and associated learning and memory behaviors (Lane and Bailey, 2005).Synonyms: NR2B3, Nuclear receptor subfamily 2 group B member 3, Retinoic acid receptor RXR-gamma, Retinoid X receptor gamma

ID gène: 6258

UniProt: P48443

Pathways: Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway