THRB anticorps (N-Term)

N° du produit ABIN371846

L’anticorps anti-THRB Monoclonal Souris est utilisé pour la détection de THRB dans des échantillons de Humain. Il a été validé pour WB.

Aperçu rapide pour THRB anticorps (N-Term) (ABIN371846)

Antigène: THRB (Thyroid Hormone Receptor, beta (THRB))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp THRB est non-conjugé

Application: Western Blotting (WB)

Clone: 2386

Détail du produit anti-THRB anticorps

Épitope: N-Term

Specificité: This antibody is specific for the ~58k THR-beta protein.

Réactivité croisée (Details): Species reactivity (tested):Human.

Attributs du produit: Synonyms: Thyroid hormone receptor beta, THR1, NR1A2, Nuclear receptor subfamily 1 group A member2

Purification: Prepared from Mouse Ascites by Ammonium Sulfate Precipitation followed by Affinity Chromatography on Protein G.

Immunogène: Peptide corresponding to amino acid residues from the N-terminal region of human thyroidhormone receptor, beta-isotype.

Isotype: IgG1

Information d'application

Indications d'application: Western Blot: 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg/mL BSA and 50 % Glycerol.

Stock: -20 °C

Stockage commentaire: Store the antibody undiluted (in aliquots) at -20 °C. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur THRB

Antigène: THRB (Thyroid Hormone Receptor, beta (THRB))

Autre désignation: THRB / ERBA2

Sujet: Thyroid hormones are essential for development of the central nervous system and deficits in these hormones during development affects such cognitive functions as learning and memory (Ambrogini et al., 2005, Chan and Kilby, 2000). Thyroid hormones exert their physiological role mainly through binding to specific nuclear receptors including the predominant isoforms of thyroid hormone receptors TR-alpha1, TR-alpha2, TR-beta1 and TR-beta2. TR-alpha1, TR-beta1 and TR-beta2 bind T3 with high affinity and also bind to thyroid hormone response elements (TREs) on chromatin to regulate the transcriptional processes in several target tissues, including adult rat brain (Constantinou et al., 2005).Synonyms: NR1A2, Nuclear receptor subfamily 1 group A member 2, THR1, Thyroid hormone receptor beta

ID gène: 7068

UniProt: P10828

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Sensory Perception of Sound