AMPD1 anticorps (AA 140-190)
Aperçu rapide pour AMPD1 anticorps (AA 140-190) (ABIN372277)
Antigène
Voir toutes AMPD1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 140-190
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Specificité
- This antibody recognizes AMPD1.
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Réactivité croisée (Details)
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Species reactivity (expected):Bovine, Chimpanzee, Dog (Canine), Monkey, Mouse, Rat and Zebrafish.
Species reactivity (tested):Human. -
Purification
- Immunoaffinity Chromatography.
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Immunogène
- Synthetic peptide corresponding to a portion of the amino acids 140-190 of Human AMPD1.
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Isotype
- IgG
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Indications d'application
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Immunohistochemistry on Paraffin Sections: 10 μg/mL. Western Blot: 0.5-2.0 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Concentration
- 0.5 mg/mL
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Buffer
- PBS containing 0.05 % Sodium Azide as preservative and 0.2 % Gelatin as stabilizer.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- AMPD1 (Adenosine Monophosphate Deaminase 1 (AMPD1))
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Autre désignation
- AMP Deaminase 1 / AMPD1
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Sujet
- AMP deaminase (AMPD) is an allosteric enzyme that plays a critical role in energy metabolism. There are three functional isoforms of AMPD. AMPD1 is the skeletal muscle-specific isoform M located in type II muscle fibers, neuromuscular junctions and in capillaries. Defects in AMPD1 are the cause of adenosine monophosphate deaminase deficiency muscle type (AMPDDM). AMPDDM is a metabolic disorder resulting in exercise-related myopathy. It is characterized by exercise-induced muscle aches, cramps, and early fatigue.Synonyms: AMP deaminase isoform M, Myoadenylate deaminase
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Poids moléculaire
- 87 kDa.
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ID gène
- 270
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NCBI Accession
- NP_000027
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UniProt
- P23109
Antigène
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