L’anticorps anti-AMPD1 Polyclonal produit chez le Lapin a été validé pour WB et IHC (p). Il convient pour la détection de AMPD1 dans des échantillons provenant de Humain, Souris, Rat, Boeuf (Vache), Singe, Poisson zèbre (Danio rerio) et Chimpanzé.
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AMPD1
Reactivité: Humain, Souris, Rat
ELISA, WB
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
Immunohistochemistry on Paraffin Sections: 5-10 μg/mL. Western Blot: 0.5-2.0 μg/mL. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Concentration
0.5 mg/mL
Buffer
PBS containing 0.05 % Sodium Azide as preservative and 0.2 % Gelatin as stabilizer.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation
Avoid repeated freezing and thawing.
Stock
4 °C/-20 °C
Stockage commentaire
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
AMP deaminase (AMPD) is an allosteric enzyme that plays a critical role in energy metabolism. There are three functional isoforms of AMPD. AMPD1 is the skeletal muscle-specific isoform M located in type II muscle fibers, neuromuscular junctions and in capillaries. Defects in AMPD1 are the cause of adenosine monophosphate deaminase deficiency muscle type (AMPDDM). AMPDDM is a metabolic disorder resulting in exercise-related myopathy. It is characterized by exercise-induced muscle aches, cramps, and early fatigue.Synonyms: AMP deaminase isoform M, Myoadenylate deaminase