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HAVCR1 anticorps (AA 200-300)

HAVCR1 Reactivité: Humain, Souris WB, IHC (p) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN372415
  • Antigène Voir toutes HAVCR1 Anticorps
    HAVCR1 (Hepatitis A Virus Cellular Receptor 1 (HAVCR1))
    Épitope
    • 12
    • 9
    • 8
    • 6
    • 6
    • 5
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 200-300
    Reactivité
    • 99
    • 48
    • 34
    • 6
    • 6
    • 5
    Humain, Souris
    Hôte
    • 102
    • 24
    • 5
    • 2
    Lapin
    Clonalité
    • 105
    • 28
    • 1
    Polyclonal
    Conjugué
    • 65
    • 15
    • 14
    • 6
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp HAVCR1 est non-conjugé
    Application
    • 93
    • 41
    • 32
    • 17
    • 16
    • 12
    • 11
    • 11
    • 11
    • 5
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Specificité
    This antibody recognizes Hepatitis A Virus Cellular Receptor 1 (HAVCR1).
    Réactivité croisée (Details)
    Species reactivity (expected):Mouse.
    Species reactivity (tested):Human.
    Purification
    Protein G Chromatography.
    Immunogène
    Synthetic peptide corresponding amino acids 200-300 of human HAVCR1.
    Isotype
    IgG
    Top Product
    Discover our top product HAVCR1 Anticorps primaire
  • Indications d'application
    Immunohistochemistry on Paraffin Sections: 2.5-5.0 μg/mL. Western blot: 1-3 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    0.5 mg/mL
    Buffer
    PBS containing 0.05 % BSA as stabilizer and 0.05 % Sodium Azide as preservative.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • Antigène
    HAVCR1 (Hepatitis A Virus Cellular Receptor 1 (HAVCR1))
    Autre désignation
    TIMD1 / HAVCR1 (HAVCR1 Produits)
    Synonymes
    anticorps HAVCR, anticorps HAVCR-1, anticorps KIM-1, anticorps KIM1, anticorps TIM, anticorps TIM-1, anticorps TIM1, anticorps TIMD-1, anticorps TIMD1, anticorps Kim1, anticorps HAVCR1, anticorps LOC100226241, anticorps AI503787, anticorps Tim1, anticorps Timd1, anticorps hepatitis A virus cellular receptor 1, anticorps hepatitis A virus cellular receptor 1 homolog, anticorps HAVCR1, anticorps Havcr1, anticorps LOC100226241
    Classe de substances
    Virus
    Sujet
    HAVCR1, a 359 A.A Class 1 integral membrane glycoprotein, is used by Hepatitis A virus to infect humans. It consists of a conserved N-terminal Cys-rich region, IgV (Immunoglobulin Variable region like) domain and a TSP-rich mucin domain in the extracellular region followed by a highly conserved tyrosine kinase phosphorylation motif in the cytoplasmic region. HAVCR1 is expressed on terminally differentiated CD4+ Th2 cells and regulates cytokine production. It plays an important role in the regulation of immune responses in the development of asthma and allergic responses. Its expression is critically upregulated in dedifferentiated kidney cells, thus indicating a possible role in regeneration of proximal tubule epithelium in Kidneys. HAVCR1 has shown to be upregulated in renal carcinomas, suggesting its role in tumor progression and metastasis.Synonyms: HAVCR-1, Hepatitis A virus cellular receptor 1, T cell immunoglobulin and mucin domain-containing protein 1, T cell membrane protein 1, TIM-1, TIM1, TIMD-1
    ID gène
    26762
    NCBI Accession
    NP_001092884
    UniProt
    Q96D42
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