SIRT7 anticorps (AA 35-51, AA 361-377)

N° du produit ABIN372439

Cet anticorps Lapin Polyclonal détecte spécifiquement SIRT7 dans WB et IHC (p). Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour SIRT7 anticorps (AA 35-51, AA 361-377) (ABIN372439)

Antigène: SIRT7 (Sirtuin 7 (SIRT7))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SIRT7 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-SIRT7 anticorps

Épitope: AA 35-51, AA 361-377

Specificité: This antibody recognizes Sirtuin Type 7 (SIRT7).

Purification: Protein G Chromatography.

Immunogène: A mixture of synthetic peptides corresponding to amino acids 35-51 and 361-377 of human SIRT7.

Isotype: IgG

Information d'application

Indications d'application: Immunohistochemistry on Paraffin Sections: 5 μg/mL. Western blot: 1-3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: PBS containing 0.2 % Gelatin as stabilizer and 0.05 % Sodium Azide as preservative.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Détails sur SIRT7

Antigène: SIRT7 (Sirtuin 7 (SIRT7))

Autre désignation: SIRT7

Sujet: SIRT7 is a human member of a family of proteins called Sirtuins (Sir2-like proteins) and are present in prokaryotes and eukaryotes. All Sir2-like proteins have a sirtuin core domain, which contains a series of sequence motifs conserved in organisms ranging from bacteria to humans. Bacterial, yeast and mammalian sirtuins are able to metabolize NAD and possibly at as mono-ADP-ribosyltransferases. The enzymatic function of sirtuins is not yet completely understood but recent reports of histone-activated Sir2-mediated NAD metabolism and NAD-activated Sir2-mediated histone deacetylation suggest a possible coupled reciprocal activation mechanism involving interactions of Sir2 with NAD and the N epsilon-acetyl-lysine groups of acetylated histones.Synonyms: NAD-dependent deacetylase sirtuin-7, S.cerevisiae, SIR2-like protein 7, SIR2L7, SIRT-7, homolog) 7, sirtuin (silent mating type information regulation 2, sirtuin 7, sirtuin type 7, sirtuin-7

ID gène: 51547

NCBI Accession: NP_057622

UniProt: Q9NRC8