Claudin 3 anticorps (C-Term)

N° du produit ABIN372578

L’anticorps anti-Claudin 3 Polyclonal Lapin est utilisé pour la détection de Claudin 3 dans des échantillons de Humain, Souris et Rat. Il a été validé pour IHC (p).

Aperçu rapide pour Claudin 3 anticorps (C-Term) (ABIN372578)

Antigène: Claudin 3 (CLDN3)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Claudin 3 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-Claudin 3 anticorps

Épitope: C-Term

Specificité: Specific to Claudin 3 (CLDN3).
Cellular Localization: Cell membrane and cytoplasmic.

Réactivité croisée (Details): Species reactivity (expected):Human and Rat.
Species reactivity (tested):Mouse.

Purification: Immunoaffinity Chromatography.

Immunogène: A synthetic peptide derived from the C-terminus of Mouse Claudin-3.

Isotype: IgG

Information d'application

Indications d'application: Immunohistochemistry on Paraffin Sections: 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 10 mM PBS, pH 7.6 containing 15 mM Sodium Azide as preservative and 0.2 % BSA,40 % Glycerol as stabilizers.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Détails sur Claudin 3

Antigène: Claudin 3 (CLDN3)

Autre désignation: Claudin-3 / CLDN3

Sujet: Claudin 1-8 proteins are a family of transmembrane proteins associated with tight junctions. Tight junctions are specialized regions of cell to cell contact, made up of network of strands to act as a molecular gasket for preventing the leakage of ions, water etc. between cells. They are abundant in luminal epithelial sheets where they maintain epithelial cell polarity. Different tissues exhibit different Claudin composition. The protein encoded by this intronless Claudin 3 gene is also a low affinity receptor for Clostridium perfringens enterotoxin, and shares amino acid sequence similarity with a putative apoptosis related protein found in rat.Synonyms: C7orf1, CPE-R2, CPE-Receptor 2, CPETR2, Clostridium perfringens enterotoxin receptor 2, RVP1

ID gène: 1365

NCBI Accession: NP_001297

UniProt: O15551

Pathways: Hepatitis C