DDC anticorps

N° du produit ABIN372608

Détail du produit anti-DDC anticorps

Antigène: DDC (Dopa Decarboxylase (Aromatic L-Amino Acid Decarboxylase) (DDC))

Reactivité: Rat, Boeuf (Vache)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DDC est non-conjugé

Application: Western Blotting (WB)

Specificité: Specific for the ~55k DDC protein.

Réactivité croisée (Details): Species reactivity (expected):Bovine.
Species reactivity (tested):Rat.

Purification: Affinity Chromatography using an AminoLink® Plus column matrix to which purified recombinant Bovine DDC was coupled.

Immunogène: SDS denatured, recombinant bovine aromatic DOPA decarboxylase (DDC) expressed in E. coli and purified from inclusion bodies.

Isotype: IgG

Information d'application

Indications d'application: Western Blot: 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg/mL BSA and 50 % Glycerol.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store the antibody undiluted (in aliquots) at-20 °C.

Détails sur DDC

Antigène: DDC (Dopa Decarboxylase (Aromatic L-Amino Acid Decarboxylase) (DDC))

Autre désignation: AADC / DDC (DDC Produits)

Synonymes: anticorps AADC, anticorps wu:fa56d05, anticorps wu:fd59h03, anticorps wu:fk20h01, anticorps zgc:65801, anticorps zgc:76929, anticorps Ddc, anticorps DdcDv, anticorps Dvir\\GJ17995, anticorps GJ17995, anticorps dvir_GLEANR_2561, anticorps Aadc, anticorps 5-HT, anticorps CG10697, anticorps DDC, anticorps DdcDm, anticorps Dmel\\CG10697, anticorps ddc, anticorps fDDC, anticorps l(2)37Bl, anticorps l(2)37Ch, anticorps l(2)k02104, anticorps dopa decarboxylase, anticorps Dopa-decarboxylase, anticorps dopa decarboxylase (aromatic L-amino acid decarboxylase), anticorps Dopa decarboxylase, anticorps dopa decarboxylase L homeolog, anticorps DDC, anticorps ddc, anticorps Ddc, anticorps Dvir\Ddc, anticorps ddc.L

Sujet: DOPA decarboxylase is an enzyme implicated in 2 metabolic pathways, synthesizing 2 important neurotransmitters: dopamine and serotonin which both play key roles in many clinical disorders, including Parkinson's disease. Following the hydroxylation of tyrosine to form L dihydroxyphenylalanine (LDOPA), catalyzed by tyrosine hydroxylase, DDC decarboxylates LDOPA to form dopamine. This neurotransmitter is found in different areas of the brain and is particularly abundant in basal ganglia. Dopamine is also produced by DDC in the sympathetic nervous system and is the precursor of the catecholaminergic hormones, noradrenaline and adrenaline in the adrenal medulla. In the nervous system, tryptophan hydroxylase produces 5 OH tryptophan, which is decarboxylated by DDC, giving rise to serotonin. DDC is a homodimeric, pyridoxal phosphate dependent enzyme.Synonyms: Aromatic-L-amino-acid decarboxylase, DOPA decarboxylase

ID gène: 24311

NCBI Accession: NP_036677

UniProt: P14173

Pathways: Dopaminergic Neurogenesis