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GABBR1 anticorps (pSer923)
GABBR1
Reactivité: Humain, Rat, Souris, Boeuf (Vache), Non-Human Primate
WB
Hôte: Lapin
Polyclonal
unconjugated
Détail du produit anti-GABBR1 anticorps
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Antigène
Voir toutes GABBR1 Anticorps
GABBR1
(gamma-aminobutyric Acid (GABA) B Receptor, 1 (GABBR1))
Épitope
Tous les épitopes à travers GABBR1 Anticorps.
pSer923
Reactivité
Toutes les réactivités sur GABBR1 Anticorps
Humain, Rat, Souris, Boeuf (Vache), Non-Human Primate
Hôte
Toutes les hôtes sur GABBR1 Anticorps
Lapin
Clonalité
Toutes les clonalités sur GABBR1 Anticorps
Polyclonal
Conjugué
Tous les conjugués à travers GABBR1 Anticorps
Cet anticorp GABBR1 est non-conjugé
Application
Tous les applications à travers GABBR1 Anticorps.
Western Blotting (WB)
Specificité
Specific for ~102k GABAB R1 phosphorylated at Ser923. Immunolabeling of the GABAB R1 band is completely blocked by lambda-phosphatase treatment.
Réactivité croisée (Details)
Species reactivity (expected):Human, Bovine, Mouse and non-Human Primates. Species reactivity (tested):Rat.
Purification
Sequential Chromatography on phospho- and dephospho-peptide affinity columns.
Immunogène
Phosphopeptide corresponding to amino acid residues surrounding the phospho-Ser923 of GABAB R1
Isotype
IgG
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Alternatives
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Information d'application
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Indications d'application
Western Blot: 1/1000. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Stockage
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Format
Liquid
Buffer
10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg/mL BSA and 50 % Glycerol.
Conseil sur la manipulation
Avoid repeated freezing and thawing.
Stock
-20 °C
Stockage commentaire
Store the antibody undiluted (in aliquots) at-20 °C.
Détails sur GABBR1
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Antigène
GABBR1
(gamma-aminobutyric Acid (GABA) B Receptor, 1 (GABBR1))
Autre désignation
GABBR1 (GABBR1 Produits )
Synonymes
anticorps GABABR1, anticorps GABBR1-3, anticorps GB1, anticorps GPRC3A, anticorps dJ271M21.1.1, anticorps dJ271M21.1.2, anticorps gabbr1, anticorps GABBR1, anticorps GABA(B)R1, anticorps GABAB1, anticorps GABAbR1, anticorps bM573K1.1, anticorps gamma-aminobutyric acid type B receptor subunit 1, anticorps gamma-aminobutyric acid (GABA) B receptor, 1a, anticorps gamma-aminobutyric acid (GABA) B receptor, 1, anticorps GABBR1, anticorps gabbr1a, anticorps gabbr1, anticorps Gabbr1
Sujet
Gamma-aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the central nervous system. There are two major classes of GABA receptors: the GABAA and the GABAB subtype of receptors. GABAB receptors are heterodimeric G protein-coupled receptors that mediate slow synaptic inhibition in the central nervous system. Phosphorylation enhances GABAB receptor effector coupling (Couve et al., 2004). Phosphorylation of Ser923 is thought to be important in the regulation of GABAB receptor function.Synonyms: GABA-B receptor 1, GABA-B-R1, GABA-BR1, GABABR1, GPRC3A, Gamma-aminobutyric acid type B receptor subunit 1, Gb1
ID gène
81657
NCBI Accession
NP_112290
UniProt
Q9Z0U4
Pathways
Positive Regulation of Peptide Hormone Secretion , cAMP Metabolic Process
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