SLC6A1 anticorps (C-Term)

N° du produit ABIN372646

Détail du produit anti-SLC6A1 anticorps

Antigène: SLC6A1 (GAT1) (GABA Transporter 1 (GAT1))

Épitope: C-Term

Reactivité: Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SLC6A1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro))

Specificité: Specific for the ~67k GAT-1 protein. Immunolabeling is blocked by the peptide used as antigen.

Réactivité croisée (Details): Species reactivity (expected):Mouse.
Species reactivity (tested):Rat.

Purification: Affinity Chromatography.

Immunogène: Peptide corresponding to amino acid residues from the C-terminal region of rat GAT-1.

Isotype: IgG

Information d'application

Indications d'application: Western Blot: 1/1000. Immunohistochemitsry: 1/100-1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg/mL BSA and 50 % Glycerol.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store the antibody undiluted (in aliquots) at-20 °C.

Détails sur SLC6A1

Antigène: SLC6A1 (GAT1) (GABA Transporter 1 (GAT1))

Autre désignation: GAT1 / SLC6A1 (GAT1 Produits)

Synonymes: anticorps GABATHG, anticorps GABATR, anticorps GAT1, anticorps A730043E01, anticorps GAT-1, anticorps Gabt, anticorps Gabt1, anticorps Gat1, anticorps XT-1, anticorps Xtrp1, anticorps si:ch211-280e18.1, anticorps si:dkey-164m14.1, anticorps slc6a1, anticorps solute carrier family 6 member 1, anticorps solute carrier family 6 (neurotransmitter transporter, GABA), member 1, anticorps solute carrier family 6 (neurotransmitter transporter, GABA), member 1, like, anticorps GABA neurotransmitter transporter 1, anticorps SLC6A1, anticorps Slc6a1, anticorps slc6a1l, anticorps slc6a1

Sujet: Gamma-aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the central nervous system, causing a hyperpolarization of the membrane through the opening of a Cl- channel associated with the GABAA receptor (GABAA-R) subtype. GABA plasma membrane transporters (GATs) influence synaptic neurotransmission by high-affinity uptake and release of GABA. To date, four distinct GABA transporters have been identified: GAT-1, GAT-2, GAT-3, and BGT-1. GAT-1, the most abundant of the transporters, is found predominantly in neurons, but also in some specialized glia (Minelli et al., 1995). GAT-1 is thought to play a key role in epileptogenesis (Zhao et al. 2003).Synonyms: GABA transporter 1, GABATR, GABT1, GAT-1, Sodium- and chloride-dependent GABA transporter 1, Solute carrier family 6 member 1

ID gène: 79212

NCBI Accession: NP_077347

UniProt: P23978