GFAP anticorps
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- Antigène Voir toutes GFAP Anticorps
- GFAP (Glial Fibrillary Acidic Protein (GFAP))
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Reactivité
- Humain, Rat, Souris
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Hôte
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Poulet
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp GFAP est non-conjugé
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Application
- Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Specificité
- Specific for the ~50 kDa GFAP protein. A lower band at ~45 kDa is a proteolytic fragment derived from the GFAP molecule.
- Réactivité croisée (Details)
- Species reactivity (tested):Human, Mouse and Rat.
- Purification
- Ig Fraction
- Immunogène
- Recombinant and purified Bovine GFAP.
- Isotype
- IgY
- Top Product
- Discover our top product GFAP Anticorps primaire
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- Indications d'application
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Western blot: 1/10,000. Immunofluorescence: 1/1,000. Immunohistochemitsry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Format
- Liquid
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- -20 °C
- Stockage commentaire
- Store the antibody undiluted (in aliquots) at-20 °C.
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- Antigène
- GFAP (Glial Fibrillary Acidic Protein (GFAP))
- Autre désignation
- GFAP (GFAP Produits)
- Synonymes
- anticorps GFAP, anticorps AI836096, anticorps cb345, anticorps etID36982.3, anticorps gfapl, anticorps wu:fb34h11, anticorps wu:fk42c12, anticorps xx:af506734, anticorps zgc:110485, anticorps glial fibrillary acidic protein, anticorps GFAP, anticorps LOC100136168, anticorps gfap, anticorps Gfap
- Sujet
- Glial Fibrillary Acidic Protein (GFAP) was discovered by Amico Bignami and co-workers as a major fibrous protein of multiple sclerosis plaques (1). It was subsequently found to be a member of the 10nm or intermediate filament (IF) family, specifically the IF family Class III, which also includes peripherin, desmin and vimentin. GFAP is strongly and specifically expressed in astrocytes and certain other astroglia in the CNS, in satellite cells, peripheral ganglia, and in non-myelinating Schwann cells in peripheral nerves. In many damage and disease states GFAP expression is heavily upregulated in astrocytes. In addition, neural stem cells frequently strongly express GFAP. Point mutations in the protein coding region of the GFAP gene lead to Alexander disease which is characterized by the presence of abnormal astrocytes containing GFAP protein aggregates known as Rosenthal fibers (2).Synonyms: Glial Fibrillary Acidic Protein
- ID gène
- 24387
- NCBI Accession
- NP_058705
- UniProt
- P47819
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