Periostin anticorps

N° du produit ABIN372701

L’anticorps Lapin Polyclonal anti-Periostin a été validé pour WB, IHC (p) et IHC (fro). Il convient pour détecter Periostin dans des échantillons de Humain, Souris, Rat, Poulet, Mammifères, Amphibien et Poisson.

Aperçu rapide pour Periostin anticorps (ABIN372701)

Antigène: Periostin (POSTN)

Reactivité: Humain, Souris, Rat, Poulet, Mammifères, Amphibien, Poisson

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Periostin est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-Periostin anticorps

Specificité: This antibody recognizes the three Periostin bands around ~93 kDa in Mouse lung extract. The immunogenic peptide is present in all known splice variants of Periostin and therefore this antibody recognizes all known molecular forms of Periostin.

Réactivité croisée (Details): Species reactivity (expected):Mammalia, Birds, Amphibians and Fishes.
Species reactivity (tested):Human, Chicken, Mouse and Rat.

Purification: Affinity Chromatography.

Immunogène: Peptide from fasciclin domain 1 of Mouse Periostin.

Isotype: IgG

Information d'application

Indications d'application: Western blot: 1/1000. Immunohistochemistry: 1/100. Immunohistochemistry on paraformaldehyde-fixed sections with a simple antigen-retrievalprotocol (incubate slides for 20 minutes at 90 °C in 10 mM sodium citrate ( pH 6.0)/ 0.1 % Tween-20).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS without preservatives.

Agent conservateur: Without preservative

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store the antibody undiluted (in aliquots) at-20 °C. For long term store the antibody (in aliquots) at -80 °C.

Détails sur Periostin

Antigène: Periostin (POSTN)

Autre désignation: Periostin

Sujet: Periostin is a matricellular protein, i.e. an extracellular matrix protein that interacts both with other ECM proteins and with cell-surface receptors. Like many other matricellular proteins, the function of periostin is important both in embryonic development and in the remodeling of adult tissues in response to pathological insults. Periostin was originally isolated as an osteoblast-specific marker that functions as a cell adhesion molecule for preosteoblasts and is thought to be involved in osteoblast recruitment, attachment and spreading (Kruzynska-Frejtag A. et al., 2004). Periostin has recently been shown to promote collagen fibrogenesis, inhibit differentiation of progenitor cells into cardiomyocytes and to be essential in maintaining the biomechanical properties of the adult myocardium (Norris et al., 2008)Synonyms: OSF-2, OSF2, Osteoblast-specific factor 2, PN, POSTN

ID gène: 10631

NCBI Accession: NP_001129406

UniProt: Q15063