RAB3A anticorps (N-Term)
Aperçu rapide pour RAB3A anticorps (N-Term) (ABIN372708)
Antigène
Voir toutes RAB3A AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- N-Term
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Specificité
- This antibody recognizes the ~27k Rab3 protein.
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Réactivité croisée (Details)
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Species reactivity (expected):Human, Mouse, Xenopus and non-Human Primates.
Species reactivity (tested):Rat. -
Purification
- Affinity Chromatography.
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Immunogène
- Peptide corresponding to amino acid residues from the N-terminal region of Rat Rab3, conjugated to keyhole limpet hemocyanin (KLH).
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Isotype
- IgG
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Indications d'application
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Western blot: 1/1,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg/mL BSA and 50 % Glycerol.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- -20 °C
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Stockage commentaire
- Store the antibody undiluted (in aliquots) at-20 °C.
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- RAB3A (RAB3A, Member RAS Oncogene Family (RAB3A))
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Autre désignation
- RAB3A
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Sujet
- Rab proteins belong to the Ras small GTPase superfamily. The GTP-binding Rab3 subfamily has 4 known isoforms: 3A, 3B, 3C, and 3D (Schluter et al., 2004). These proteins are expressed in highest concentrations in brain and endocrine tissues and involved in regulated exocytosis of hormones and neurotransmitters (Coppola et al., 2002). Specifically, Rab3's are thought to play a key role in presynaptic vesicle trafficking and priming (Schluter et al., 2006).Synonyms: RAB3A, RAB3B, RAB3C, RAB3D, Rab-3A, Rab-3B, Rab-3C, Rab-3D, Ras-related protein Rab-3A, Ras-related protein Rab-3B, Ras-related protein Rab-3C, Ras-related protein Rab-3D
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ID gène
- 25531
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NCBI Accession
- NP_037150
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UniProt
- P63012
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Pathways
- Synaptic Membrane, Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport
Antigène
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