SYT1 anticorps (pThr202)

N° du produit ABIN372724

Détail du produit anti-SYT1 anticorps

Antigène: SYT1 (Synaptotagmin I (SYT1))

Épitope: pThr202

Reactivité: Humain, Rat, Souris, Boeuf (Vache), Poulet, Chien, Poisson zèbre (Danio rerio), Non-Human Primate

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SYT1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Dot Blot (DB)

Specificité: This antibody recognizes the ~60k-62k synaptotagmin protein phosphorylated at Thr202 in Western Blots of Rat brain lysate. The immunolabeling is completely eliminated by lambda-phosphatase treatment.

Réactivité croisée (Details): Species reactivity (expected):Human, Bovine, Canine, Chicken, Mouse, non-Human Primate and Zebrafish.
Species reactivity (tested):Rat.

Purification: Sequential Chromatography on phospho- and dephosphopeptide affinity columns.

Immunogène: Phosphopeptide corresponding to amino acid residues surrounding the phospho-Thr202 of Synaptotagmin.

Isotype: IgG

Information d'application

Indications d'application: Dot blot: 1/1,000. Western blot: 1/1,000. Immunohistochemistry: 1/400.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg/mL BSA and 50 % Glycerol.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store the antibody undiluted (in aliquots) at-20 °C.

Détails sur SYT1

Antigène: SYT1 (Synaptotagmin I (SYT1))

Autre désignation: Synaptotagmin-1 (SYT1 Produits)

Synonymes: anticorps P65, anticorps SVP65, anticorps SYT, anticorps CG3139, anticorps D. Syt I, anticorps DSYT, anticorps DSYT2, anticorps DSypt, anticorps DSyt, anticorps Dmel\\CG3139, anticorps Droso1, anticorps Dsyt2, anticorps SYT I, anticorps SYT1, anticorps Syt, anticorps Syt 1, anticorps Syt I, anticorps Syt-1, anticorps SytI, anticorps dSYT, anticorps dsyt1, anticorps dsytI, anticorps l(2)23AB1, anticorps l(2)23Ba, anticorps l(2)k05909, anticorps syt, anticorps syt 1, anticorps syt I, anticorps syt-1, anticorps syt1, anticorps sytI, anticorps AW124717, anticorps G630098F17Rik, anticorps Syti, anticorps GB20036, anticorps DKFZP459P193, anticorps svp65, anticorps p65, anticorps wu:fj41c01, anticorps wu:fk56d05, anticorps zgc:92899, anticorps synaptotagmin 1, anticorps Synaptotagmin 1, anticorps synaptotagmin I, anticorps synaptotagmin-1, anticorps synaptotagmin, p65, anticorps synaptotagmin Ia, anticorps synaptotagmin 1 L homeolog, anticorps SYT1, anticorps Syt1, anticorps Tsp_06980, anticorps Tsp_08220, anticorps syt1, anticorps LOC100533340, anticorps syt1a, anticorps syt1.L

Sujet: Synaptotagmin is widely regarded as the primary calcium sensor for synaptic vesicle exocytosis (Fernandez-Chacon et al., 2001, Wang et al., 2003). Moreover, recent studies indicate that the protein also plays a key role in endocytosis (Poskanzer et al., 2003). Synaptotagmin can be phosphorylated by multiple protein kinases and this may play a key role in modulation of synaptotagmin's ability to influence both the exocytotic and endocytotic components of synaptic transmission (Hilfiker et al., 1999, Lee et al., 2004).Synonyms: SYT1, SYT2, SYT3, SYT4, SYT5

ID gène: 6857

NCBI Accession: NP_001129277

UniProt: P21579

Pathways: Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport