SYT1 anticorps (pSer309)

N° du produit ABIN372725

L’anticorps Lapin Polyclonal anti-SYT1 a été validé pour WB, IHC (fro) et DB. Il convient pour détecter SYT1 dans des échantillons de Humain, Rat, Souris, Boeuf (Vache), Poulet, Chien, Poisson zèbre (Danio rerio) et Non-Human Primate.

Aperçu rapide pour SYT1 anticorps (pSer309) (ABIN372725)

Antigène: SYT1 (Synaptotagmin I (SYT1))

Reactivité: Humain, Rat, Souris, Boeuf (Vache), Poulet, Chien, Poisson zèbre (Danio rerio), Non-Human Primate

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SYT1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Dot Blot (DB)

Détail du produit anti-SYT1 anticorps

Épitope: pSer309

Specificité: This antibody recognizes the ~60k-62k Synaptotagmin protein phosphorylated at Ser309 in Western Blots of Rat brain lysate.

Réactivité croisée (Details): Species reactivity (expected):Human, Bovine, Canine, Chicken, Mouse, non-Human Primates and Zebrafish.
Species reactivity (tested):Rat.

Purification: Sequential Chromatography on phospho- and dephosphopeptide affinity columns.

Immunogène: Phosphopeptide corresponding to amino acid residues surrounding the phospho-Ser309 of Synaptotagmin.

Isotype: IgG

Information d'application

Indications d'application: Dot blot: 1/1,000. Western blot: 1/1,000. Immunohistochemistry: 1/400.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg/mL BSA and 50 % Glycerol.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store the antibody undiluted (in aliquots) at-20 °C.

Détails sur SYT1

Antigène: SYT1 (Synaptotagmin I (SYT1))

Autre désignation: Synaptotagmin-1

Sujet: Synaptotagmin is widely regarded as the primary calcium sensor for synaptic vesicle exocytosis (Fernandez-Chacon et al., 2001, Wang et al., 2003). Moreover, recent studies indicate that the protein also plays a key role in endocytosis (Poskanzer et al., 2003). Synaptotagmin can be phosphorylated by multiple protein kinases and this may play a key role in modulation of synaptotagmin's ability to influence both the exocytotic and endocytotic components of synaptic transmission (Hilfiker et al., 1999, Lee et al., 2004).Synonyms: SYT1, SYT2, SYT3, SYT4, SYT5

ID gène: 6857

NCBI Accession: NP_001129277

UniProt: P21579

Pathways: Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport