TAO Kinase 2 anticorps (pSer181)

N° du produit ABIN372726

Cet anticorps anti-TAO Kinase 2 est un anticorps Lapin Polyclonal détectant TAO Kinase 2 dans WB. Adapté pour Humain, Souris, Rat, Chien, Xenopus laevis, Pinson et Poisson zèbre (Danio rerio).

Aperçu rapide pour TAO Kinase 2 anticorps (pSer181) (ABIN372726)

Antigène: TAO Kinase 2 (TAOK2)

Reactivité: Humain, Souris, Rat, Chien, Xenopus laevis, Pinson, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TAO Kinase 2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-TAO Kinase 2 anticorps

Épitope: pSer181

Specificité: Specific for the ~120k TAO2 phosphorylated at Ser181 in Western blots. Immunolabeling is completely eliminated by treatment with lambda-phosphatase.

Réactivité croisée (Details): Species reactivity (expected):Canine, Finch, Xenopus and Zebrafish.
Species reactivity (tested):Human, Mouse and Rat.

Purification: Affinity Chromatography via sequential chromatography on phospho- and dephosphopeptide affinity columns.

Immunogène: Phosphopeptide corresponding to amino acid residues surrounding the phospho-Ser181 of TAO2.

Isotype: IgG

Information d'application

Indications d'application: Western blot: 1/1,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg/mL BSA and 50 % Glycerol.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store the antibody undiluted (in aliquots) at-20 °C.

Détails sur TAO Kinase 2

Antigène: TAO Kinase 2 (TAOK2)

Sujet: In vitro, TAO (thousand and one amino acid) protein kinase 2 (TAO2) activates MAP/ERK kinases (MEKs) 3, 4, and 6 toward their substrates p38 MAP kinase JNK/SAPK (Chen et al., 1999, Chen and Cobb, 2001). This and more recent work has led to the proposal that the TAO protein kinases play an essential role in signaling from physiological agonists to the stress-responsive p38 MAPKs (Chen et al., 2003). Autophosphorylation of TAO may play a role in the mechanism of TAO activation. The MEK binding domain of TAO is autophosphorylated on both serine and threonine residues and Ser181 is located within this domain.Synonyms: KFC-C, KIAA0881, Kinase from chicken homolog C, MAP3K17, PSK-1, PSK1, Prostate-derived STE20-like kinase 1, Serine/threonine-protein kinase TAO2, Thousand and one amino acid protein 2, UNQ2971/PRO7431

ID gène: 9344

NCBI Accession: NP_004774

UniProt: Q9UL54

Pathways: Cell-Cell Junction Organization