SNAP25 anticorps (C-Term)
Aperçu rapide pour SNAP25 anticorps (C-Term) (ABIN372760)
Antigène
Voir toutes SNAP25 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- C-Term
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Specificité
- Recognizes Synaptosomal Associated Protein 25 (SNAP25).
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Réactivité croisée (Details)
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Species reactivity (expected):Canine (Dog), Mouse and Rat.
Species reactivity (tested):Human. -
Purification
- Immunoaffinity Chromatography.
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Immunogène
- Synthetic peptide (DEANQRATKMLGSG) -KLH conjugated from C-terminus of Human SNAP25.
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Isotype
- IgG
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Indications d'application
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ELISA: 1/32000. Western Blot: 0.01-0.03 μg/mL. Immunohistochemistry on Paraffin Sections: 2.5 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Concentration
- 0.5 mg/mL
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Buffer
- Tris Saline Buffer, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- SNAP25 (Synaptosomal-Associated Protein, 25kDa (SNAP25))
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Autre désignation
- SNAP25
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Sujet
- SNAP25 (Synaptosome-Associated Protein of 25 kDa) is a membrane bound, pre-synaptic nerve terminal protein that plays an essential role in synaptic vesicle fusion and exocytosis. It is part of the SNARE core complex containing SNAP25, VAMP2 and STX1A. SNAP25 is involved in the molecular regulation of neurotransmitter release. It is thought to play an important role in the synaptic function of specific neuronal systems and it associates with proteins involved in vesicle docking and membrane fusion. SNAP25 exists as two alternatively spliced isoforms, SNAP25A and SNAP25B. These isoforms are differentially expressed in neurons and neuroendocrine cells and they differ by 9 amino acids in the central portion of the protein.Synonyms: RIC4, SNAP, SNAP-25, SUP, Super Protein, Synaptosomal-associated 25 kDa protein, Synaptosomal-associated protein 25, ric-4
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ID gène
- 6616
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NCBI Accession
- NP_003072
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UniProt
- P60880
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Pathways
- Positive Regulation of Peptide Hormone Secretion, Hormone Transport, Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport
Antigène
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