PNPLA2 anticorps (Internal Region)

N° du produit ABIN372772

Cet anticorps Chèvre Polyclonal détecte spécifiquement PNPLA2 dans IHC (p) et EIA. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour PNPLA2 anticorps (Internal Region) (ABIN372772)

Antigène: PNPLA2 (Patatin-Like phospholipase Domain Containing 2 (PNPLA2))

Reactivité: Humain, Souris, Rat

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp PNPLA2 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Détail du produit anti-PNPLA2 anticorps

Épitope: Internal Region

Specificité: Recognizes Patatin-Like Phospholipase Domain Containing 2 (PNPLA2).

Réactivité croisée (Details): Species reactivity (expected):Human and Rat.
Species reactivity (tested):Mouse.

Purification: Immunoaffinity Chromatography.

Immunogène: Synthetic peptide (C-NIIEVSKEARKR) from an internal region of Mouse PNPLA2.

Isotype: IgG

Information d'application

Indications d'application: ELISA: 1/32000. Immunohistochemistry on Paraffin Sections: 2.5 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Tris saline buffer, pH 7.3 containing 0.5 % BSA as stabilizer and 0.02 % Sodium Azide as preservative.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Détails sur PNPLA2

Antigène: PNPLA2 (Patatin-Like phospholipase Domain Containing 2 (PNPLA2))

Autre désignation: PNPLA2 / ATGL

Sujet: Adipose triglyceride lipase (ATGL) may function as a lipase and play a role in the adaptive response to a low energy state, such as fasting, by providing fatty acids to other tissues for oxidation. In addition, decreased expression of desnutrin in obesity models suggests its possible contribution to the pathophysiology of obesity. ATGL catalyzes the initial step in triglyceride hydrolysis in mammalian adipose tissue. ATGL contains a patatin domain common to plant acyl hydrolases. ATGL is highly expressed in adipose tissue of mice and humans. It exhibits high substrate specificity for triacylglycerol and is associated with lipid droplets. Inhibition of ATGL markedly decreases total adipose acyl hydrolase activity. Thus, ATGL and HSL coordinately catabolize stored triglycerides in adipose tissue of mammalsSynonyms: Adipose triglyceride lipase, Calcium-independent phospholipase A2, Desnutrin, FP17548, IPLA2-zeta, Patatin-like phospholipase domain-containing protein 2, Pigment epithelium-derived factor, TTS2.2, Transport-secretion protein 2

ID gène: 57104

NCBI Accession: NP_065109

UniProt: Q96AD5