IL27 anticorps (N-Term)
Aperçu rapide pour IL27 anticorps (N-Term) (ABIN372855)
Antigène
Voir toutes IL27 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- N-Term
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Specificité
- This antibody recognizes Interleukin 27 (IL27).
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Réactivité croisée (Details)
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Species reactivity (expected):Mouse.
Species reactivity (tested):Human. -
Purification
- Immunoaffinity Chromatography
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Immunogène
- Synthetic peptide from Human IL27
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Isotype
- IgG
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Indications d'application
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Immunohistochemistry on paraffin sections: 5 μg/mL. Immunocytochemistry. Western blot: 2 - 4 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Buffer
- PBS, 0.02 % Sodium Azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- IL27 (Interleukin-27 Subunit alpha (IL27))
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Autre désignation
- Interleukin-27 / IL27A
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Sujet
- IL27 is a recently discovered member of the IL6/IL12 family of proinflammatory and immunoregulatory cytokines. It exists as a heterodimer composed of the p40-related protein EBI3 and an IL12 p35-related protein termed p28. IL27 is produced after activation by antigen-presenting cells and induces proliferation of naive but not memory CD4+ T-cells. It acts by binding to its receptor WSX-1 and gp130 which results in the activation of a Jak/STAT signaling cascade, suggesting the IL27 is involved in the regulation of immune processes.Synonyms: IL-27 subunit alpha, IL-30, IL27-A, IL30, Interleukin-30, p28
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ID gène
- 246778
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NCBI Accession
- NP_663634
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UniProt
- Q8NEV9
Antigène
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