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IL27 anticorps (N-Term)

Cet anticorps anti-IL27 est un anticorps Lapin Polyclonal détectant IL27 dans WB, IHC (p) et IF. Adapté pour Humain et Souris.
N° du produit ABIN372855

Aperçu rapide pour IL27 anticorps (N-Term) (ABIN372855)

Antigène

Voir toutes IL27 Anticorps
IL27 (Interleukin-27 Subunit alpha (IL27))

Reactivité

  • 17
  • 13
  • 13
Humain, Souris

Hôte

  • 17
  • 6
Lapin

Clonalité

  • 17
  • 6
Polyclonal

Conjugué

  • 14
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp IL27 est non-conjugé

Application

  • 11
  • 7
  • 6
  • 6
  • 3
  • 3
  • 3
  • 2
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
  • Épitope

    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    Specificité

    This antibody recognizes Interleukin 27 (IL27).

    Réactivité croisée (Details)

    Species reactivity (expected):Mouse.
    Species reactivity (tested):Human.

    Purification

    Immunoaffinity Chromatography

    Immunogène

    Synthetic peptide from Human IL27

    Isotype

    IgG
  • Indications d'application

    Immunohistochemistry on paraffin sections: 5 μg/mL. Immunocytochemistry. Western blot: 2 - 4 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    Restrictions

    For Research Use only
  • Buffer

    PBS, 0.02 % Sodium Azide

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Conseil sur la manipulation

    Avoid repeated freezing and thawing.

    Stock

    4 °C/-20 °C

    Stockage commentaire

    Store undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • Antigène

    IL27 (Interleukin-27 Subunit alpha (IL27))

    Autre désignation

    Interleukin-27 / IL27A

    Sujet

    IL27 is a recently discovered member of the IL6/IL12 family of proinflammatory and immunoregulatory cytokines. It exists as a heterodimer composed of the p40-related protein EBI3 and an IL12 p35-related protein termed p28. IL27 is produced after activation by antigen-presenting cells and induces proliferation of naive but not memory CD4+ T-cells. It acts by binding to its receptor WSX-1 and gp130 which results in the activation of a Jak/STAT signaling cascade, suggesting the IL27 is involved in the regulation of immune processes.Synonyms: IL-27 subunit alpha, IL-30, IL27-A, IL30, Interleukin-30, p28

    ID gène

    246778

    NCBI Accession

    NP_663634

    UniProt

    Q8NEV9
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