LRRC7
Reactivité: Souris, Rat
WB
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
Immunohistochemistry on paraffin sections: 5 μg/mL. Western blot: 1 μg/mL. ELISA: 1 μg/mL. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Buffer
PBS, 0.01 % sodium azide, 50 % glycerol
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation
Avoid repeated freezing and thawing.
Stock
4 °C/-20 °C
Stockage commentaire
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
The attachment of the lamins to the inner nuclear membrane appears to occur through their association with 4 related integral membrane proteins called Lamin Associated Polypeptides (LAPs). LAP 1A, 1B & 1C share a high degree of sequence homology while LAP 2 is distinct from the others. LAP1 is a brain specific protein that may be involved in the organization of synaptic cell-cell contacts. LAP1 interacts with CAMKII and CTNND2/Catenin delta-2 and forms a complex with N-cadherin through CTNND2. There are three named isforms produced by alternative splicing.Synonyms: Densin-180, KIAA1365, LAP1, LRRC7, Leucine-rich repeat-containing protein 7