SH3GLB1 anticorps (C-Term)

N° du produit ABIN374106

Cet anticorps anti-SH3GLB1 est un anticorps Chèvre Polyclonal détectant SH3GLB1 dans WB. Adapté pour Humain, Souris, Rat, Boeuf (Vache) et Chien.

Aperçu rapide pour SH3GLB1 anticorps (C-Term) (ABIN374106)

Antigène: SH3GLB1 (SH3-Domain GRB2-Like Endophilin B1 (SH3GLB1))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp SH3GLB1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-SH3GLB1 anticorps

Épitope: C-Term

Séquence: C-QKGKVPITYL ELLN

Specificité: This antibody detects BIF1 / Endophilin-B1 at C-term.

Purification: Ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide

Immunogène: Peptide from the C Terminus of the protein sequence according to NP_057093.1 Genename: SH3GLB1

Information d'application

Indications d'application: Peptide ELISA: Limit dilution 1: 32000. Western blot: 0.3-1.0 μg/mL. Approx 38 kDa band observed in lysates of Human T cell lineJurkat and in Human Lung and Placenta (calculated MW of 40.8 kDa according toNP_057093.1).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C.

Détails sur SH3GLB1

Antigène: SH3GLB1 (SH3-Domain GRB2-Like Endophilin B1 (SH3GLB1))

Autre désignation: Endophilin-B1

Sujet: Bif is a member of the endophilin B protein family and may be an important component of the mitochondrial pathway for apoptosis, as a novel Bax/Bak activator. The loss of this proapoptotic molecule may contribute to tumorigenesis. Endophilins have been proposed to play roles in membrane trafficking reactions through interactions with endocytic protein via physical or chemical modifications of the membrane bilayer, particularly in presynaptic vesicle trafficking at nerve terminals. Bif (Endophilin B1), like endophilins A, binds to palmitoyl CoA and exhibits lysophosphatidic acid acyl transferase activity.Synonyms: BIF1, Bax-interacting factor 1, Bif-1, KIAA0491, SH3 domain-containing GRB2-like protein B1, SH3GLB1

ID gène: 51100

NCBI Accession: NP_057093

UniProt: Q9Y371

Pathways: Autophagy