BAIAP2 anticorps (C-Term, Isoform 3)

N° du produit ABIN374111

L’anticorps anti-BAIAP2 Polyclonal Chèvre est utilisé pour la détection de BAIAP2 dans des échantillons de Humain, Chien et Boeuf (Vache). Il a été validé pour WB.

Aperçu rapide pour BAIAP2 anticorps (C-Term, Isoform 3) (ABIN374111)

Antigène: BAIAP2 (BAI1-Associated Protein 2 (BAIAP2))

Reactivité: Humain, Chien, Boeuf (Vache)

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp BAIAP2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-BAIAP2 anticorps

Épitope: C-Term, Isoform 3

Séquence: C-SMSSADVEVA RF

Specificité: This antibody will recognise only one of three reported isoforms (NP_006331.1) (Isofom 3).

Réactivité croisée (Details): Species reactivity (expected):Canine (Dog), Bovine.
Species reactivity (tested):Human.

Purification: Ammonium Sulphate precipitation followed by antigen Affinity Chromatography using the immunizing peptide

Immunogène: Peptide from the C-Terminus of the protein sequence according to NP_006331.1. Genename: BAIAP2

Information d'application

Indications d'application: Peptide ELISA: Limit dilution 1: 16000. Western blot: 1-3 μg/mL. Approx 55 kDa band observed in Human Brain (Cerebellum andFrontal Cortex) lysates (calculated MW of 57.5 kDa according to NP_006331.1).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C.

Détails sur BAIAP2

Antigène: BAIAP2 (BAI1-Associated Protein 2 (BAIAP2))

Autre désignation: BAIAP2

Sujet: BAIAP2, a target of p53, has been identified as a brain-specific angiogenesis inhibitor (BAI1)-binding protein. This interaction at the cytoplasmic membrane is crucial to the function of this protein, which may be involved in neuronal growth-cone guidance. This protein functions as an insulin receptor tyrosine kinase substrate and suggests a role for insulin in the central nervous system. This protein has also been identified as interacting with the dentatorubral-pallidoluysian atrophy gene, which is associated with an autosomal dominant neurodegenerative disease. It also associates with a downstream effector of Rho small G proteins, which is associated with the formation of stress fibers and cytokinesis.Synonyms: BAI-associated protein 2, BAI1-associated protein 2, BAP2, Brain-specific angiogenesis inhibitor 1-associated protein 2, FLAF3, Fas ligand-associated factor 3, IRS-58, IRSp53, IRSp53/58, Insulin receptor substrate p53, Insulin receptor substrate p53/p58, Insulin receptor substrate protein of 53 kDa

ID gène: 10458

NCBI Accession: NP_006331

UniProt: Q9UQB8